Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23500799 | 0.73 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5217257 | 0.69 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5218358 | 0.67 | PLA2G2A (0.59) | ALDH1A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5853388 | 0.67 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7934718 | 0.67 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5221285 | 0.66 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28406303 | 0.66 | LMNA (0.54) | ALDH1A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL440026 | 0.66 | ALDH1A1 (0.36) | ALDH1A1HSD17B10HPGDUSP2KMT2A | |
| SCHEMBL5219110 | 0.66 | ALDH1A1 (0.71) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3678191 | 0.66 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980220-B2 | Molecular probe for imaging of pancreatic islets and use of the same | KYOTO UNIVERSITY (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20110206605-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | KYOTO UNIVERSITY (JP) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110206605-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | IAPP, NGLY1, GPR119 | ALDH1A1 4779/4885HSD17B10 4300/4885CYP1A2 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.