Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405573 | 0.88 | CCR5 (0.42) | PTGER1CYP2D6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL914632 | 0.87 | KMT2A (0.47) | CYP2D6ALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL4411253 | 0.78 | LMNA (0.35) | PTGER1CYP2D6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL914650 | 0.75 | MEN1 (0.47) | CYP2D6ALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL12975788 | 0.75 | ALOX15 (0.34) | PTGER1ALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL4409139 | 0.73 | ADRB3 (0.41) | PTGER1ADRB3MEN1KMT2A | |
| SCHEMBL6963102 | 0.68 | KDM4E (0.38) | CYP2D6ALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL914267 | 0.68 | KDM4E (0.38) | CYP2D6ALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL4551166 | 0.67 | LMNA (0.42) | ALDH1A1ADRB3LMNAMAPTHTR1A | |
| SCHEMBL4405571 | 0.67 | KDM4E (0.39) | ALDH1A1HSD17B10KDM4EADRB3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |