Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283048 | 0.94 | RORC (0.35) | ALDH1A1HTTESR1GPR84PTPN5 | |
| SCHEMBL16182145 | 0.94 | RORC (0.35) | ALDH1A1HTTESR1GPR84PTPN5 | |
| SCHEMBL438804 | 0.91 | RORC (0.35) | ALDH1A1ESR1GPR84PTPN5ENPP1 | |
| SCHEMBL438808 | 0.82 | HDAC8 (0.42) | ALDH1A1HTTKDM4EMEN1CYP1A2 | |
| SCHEMBL438674 | 0.81 | MAPK1 (0.39) | ALDH1A1GPR84ENPP1RORCMAPK1 | |
| SCHEMBL438809 | 0.81 | CYP11B1 (0.37) | ALDH1A1HTTGPR84ENPP1RORC | |
| SCHEMBL440660 | 0.80 | HSD17B1 (0.39) | ALDH1A1HTTESR1KDM4ESMN1; SMN2 | |
| SCHEMBL438816 | 0.79 | ALDH1A1 (0.32) | ALDH1A1HTTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL440772 | 0.77 | ALOX5 (0.46) | ALDH1A1HTT | |
| SCHEMBL15063516 | 0.76 | SMN1; SMN2 (0.44) | ALDH1A1HTTKIF11RORCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9564597-B2 | Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-02-07 | — | — | US | disclosed |
| US-9564597-B2 | Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-02-07 | — | — | US | disclosed |
| US-20150243899-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150243899-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-08-27 | — | — | US | disclosed |
| US-8993127-B2 | Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993127-B2 | Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-03-31 | — | — | US | disclosed |
| EP-2428512-B1 | Fluorene compound, light-emitting element, light-emitting device, electronic device and lighting device | SEMICONDUCTOR ENERGY LAB (JP) | 2014-10-22 | — | — | EP | disclosed |
| US-20120061714-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-03-15 | — | — | US | disclosed |
| US-20120061714-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150243899-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | CYP1A1, CYP1B1, DRD1 | ALDH1A1 10/4885HTT 2663/4885ESR1 138/4885 |
| US-20120061714-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | CYP1A1, CYP1B1, DRD1 | ALDH1A1 10/4885HTT 2663/4885ESR1 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.