Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283048 | 1.00 | RORC (0.35) | RORCALDH1A1HTTESR1GPR84 | |
| SCHEMBL440108 | 0.94 | ALDH1A1 (0.35) | RORCALDH1A1HTTESR1GPR84 | |
| SCHEMBL438804 | 0.90 | RORC (0.35) | RORCALDH1A1ESR1GPR84CYP2C9 | |
| SCHEMBL438808 | 0.89 | HDAC8 (0.42) | ALDH1A1HTTCYP2C9CYP1A2CYP2D6 | |
| SCHEMBL438674 | 0.88 | MAPK1 (0.39) | RORCALDH1A1GPR84CYP2C9ENPP1 | |
| SCHEMBL438809 | 0.87 | CYP11B1 (0.37) | RORCALDH1A1HTTGPR84CYP2C9 | |
| SCHEMBL440772 | 0.83 | ALOX5 (0.46) | ALDH1A1HTT | |
| SCHEMBL1191671 | 0.80 | CRHBP (0.35) | RORCALDH1A1ESR1CYP2C9CYP1A2 | |
| SCHEMBL9285749 | 0.79 | ALDH1A1 (0.42) | ALDH1A1CYP2C9KIF11CYP1A2CYP2D6 | |
| SCHEMBL440660 | 0.79 | HSD17B1 (0.39) | ALDH1A1HTTESR1CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428512-B1 | Fluorene compound, light-emitting element, light-emitting device, electronic device and lighting device | SEMICONDUCTOR ENERGY LAB (JP) | 2014-10-22 | — | — | EP | disclosed |