SCHEMBL440112

SCHEMBL440112

CO[Si](CO)(CO)CCCNCCC[Si](OC)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18099451 0.85 CA12 (0.41) ALDH1A1HSD17B10LMNA
SCHEMBL19822477 0.84 ALDH1A1 (0.38) ALDH1A1LMNA
SCHEMBL49693 0.83 LMNA (0.39) ALDH1A1LMNA
SCHEMBL1818057 0.82 LMNA (0.35) ALDH1A1LMNA
SCHEMBL5612459 0.82 KDM4E (0.39) ALDH1A1HSD17B10LMNA
SCHEMBL1896378 0.82 ALDH1A1 (0.41) ALDH1A1HSD17B10LMNA
Ammonia Solution, Strong SCHEMBL5681835 0.81 LMNA (0.38) ALDH1A1LMNA
SCHEMBL4624700 0.81 LMNA (0.38) ALDH1A1LMNA
SCHEMBL1931026 0.81 LMNA (0.38) ALDH1A1LMNA
SCHEMBL29534835 0.81 LMNA (0.38) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9944770-B2 Moisture curable compound with thiourea MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-04-17 US disclosed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US disclosed
US-20170306096-A1 MOISTURE CURABLE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2017-10-26 US disclosed
US-20170260335-A1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MATERIALS INC. 2017-09-14 US disclosed
US-20170174840-A1 MOISTURE CURABLE SILICONE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2017-06-22 US disclosed
US-9663657-B2 Moisture curable organopolysiloxane compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-05-30 US disclosed
US-9663621-B2 Moisture curable compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-05-30 US disclosed
US-9663620-B2 Catalyst for synthesis of siloxanes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-05-30 US disclosed
US-9527959-B2 Moisture curable organopolysiloxane composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-12-27 US disclosed
US-20160369061-A1 MOISTURE CURABLE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-12-22 US disclosed
US-20160347910-A1 CATALYST FOR SYNTHESIS OF SILOXANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-12-01 US disclosed
US-20160200880-A1 MOISTURE CURABLE COMPOSITION WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-07-14 US disclosed
US-20160200875-A1 MOISTURE CURABLE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-07-14 US disclosed
US-20160137816-A1 MOISTURE CURABLE COMPOUND WITH THIOUREA MOMENTIVE PERFORMANCE MATERIALS INC. 2016-05-19 US disclosed
US-20150094421-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2015-04-02 US disclosed
US-20150038632-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2015-02-05 US disclosed
US-8937141-B2 Moisture curable organopolysiloxane composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-01-20 US disclosed
US-20150005443-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2015-01-01 US disclosed
US-20140350175-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2014-11-27 US disclosed
US-20120065308-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2012-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170306096-A1 MOISTURE CURABLE COMPOSITIONS DOT1L, EHMT2, CDH1 ALDH1A1 595/4885HSD17B10 3280/4885LMNA 2581/4885
US-20160200875-A1 MOISTURE CURABLE COMPOSITIONS RNMT, DOT1L, SAT1 ALDH1A1 2335/4885HSD17B10 4536/4885LMNA 3138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.