SCHEMBL4401320

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL831034	0.84	HPGD (0.51)	CA1CA2HPGDLMNAKEAP1
	SCHEMBL10772858	0.81	HPGD (0.53)	CA1CA2HPGDLMNAKEAP1
	SCHEMBL6202161	0.79	HPGD (0.56)	CA1CA2HPGDLMNAKEAP1
	SCHEMBL832208	0.78	HPGD (0.50)	CA1CA2HPGDLMNAKEAP1
	SCHEMBL3923476	0.75	CA1 (0.58)	CA1CA2HPGDLMNAKEAP1
	SCHEMBL15672897	0.74	CA2 (0.56)	CA1CA2HPGDLMNAKEAP1
	SCHEMBL6533144	0.74	CA1 (0.56)	CA1CA2HPGDLMNAKEAP1
	Acetic Acid SCHEMBL27557152	0.74	HPGD (0.69)	CA1CA2HPGDLMNAKEAP1
	SCHEMBL1020182	0.74	CA1 (0.56)	CA1CA2KEAP1CA12CA9
	SCHEMBL4557719	0.73	CYP2C19 (0.43)	CA1CA2LMNACA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.