Sugi Predict

Sugi Predict / Compounds / SCHEMBL1020182

SCHEMBL1020182

SCHEMBL1020182

NC(=O)S(=O)(=O)Nc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 4/20 0.56
▸ CA2 P00918 4/20 0.56
▸ KEAP1 Q14145 3/20 0.50
▸ IL1RN P18510 1/20 0.48
▸ ERAP1 Q9NZ08 1/20 0.48
▸ TMPRSS6 Q8IU80 2/20 0.47
▸ KMT2A Q03164 2/20 0.46
▸ MEN1 O00255 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ PKM P14618 1/20 0.45
▸ CA12 O43570 3/20 0.44
▸ CA9 Q16790 3/20 0.44
▸ MAPT P10636 2/20 0.44
▸ TSHR P16473 2/20 0.44
▸ POLB P06746 2/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ PARP1 P09874 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ BLM P54132 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10766214 0.82 KEAP1 (0.54) CA1CA2KEAP1IL1RNERAP1
SCHEMBL29092698 0.78 KEAP1 (0.56) CA1CA2KEAP1IL1RNERAP1
SCHEMBL11788594 0.78 CA1 (0.50) CA1CA2KEAP1IL1RNERAP1
SCHEMBL3053464 0.77 MMP2 (0.54) CA1CA2KEAP1IL1RNERAP1
SCHEMBL10611173 0.77 KEAP1 (0.48) CA1CA2KEAP1IL1RNERAP1
SCHEMBL10955158 0.77 TP53 (0.52) CA1CA2KEAP1IL1RNERAP1
SCHEMBL3802959 0.75 CA1 (0.52) CA1CA2KEAP1IL1RNERAP1
SCHEMBL9231787 0.74 KEAP1 (0.56) CA1CA2KEAP1IL1RNERAP1
SCHEMBL4401320 0.74 CA1 (0.50) CA1CA2KEAP1IL1RNERAP1
SCHEMBL13281775 0.74 KEAP1 (0.50) CA1CA2KEAP1IL1RNERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1226127-B1 SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES BASF SE (DE) 2009-07-01 — — EP claimed
CN-1171875-C Uracil substituted phenyl sulfamoyl carboxamides �����ɷ� 2004-10-20 — — CN claimed
US-20030224941-A1 Uracil substituted phenyl sulfamoyl carboxamides CARLSEN MARIANNE (US) 2003-12-04 — — US claimed
US-6534492-B2 Herbicidal phenylsulfamoyl carboxamides BASF AKTIENGESELLSCHAFT (DE) 2003-03-18 — — US claimed
EP-1226127-A2 URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES BASF AKTIENGESELLSCHAFT (DE) 2002-07-31 — — EP claimed
US-20020045550-A1 Uracil substituted phenyl sulfamoyl carboxamides INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) 2002-04-18 — — US claimed
WO-2001083459-A2 URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES BASF AKTIENGESELLSCHAFT (DE) 2001-11-08 — — WO claimed
CN-117534629-A Triazinone compound and preparation method and application thereof 贵州大学 2024-02-09 — — CN disclosed
US-8703650-B2 Liquid suspension concentrate formulations containing saflufenacil BASF SE (DE) 2014-04-22 — — US disclosed
US-8541611-B2 Bifunctional phenyl iso(thio)cyanates, processes and intermediates products for their preparation BASF AKTIENGESELLSCHAFT (DE) 2013-09-24 — — US disclosed
US-20120310010-A1 Method for producing sulfonamides BASF SE (DE) 2012-12-06 — — US disclosed
US-20120302444-A1 LIQUID SUSPENSION CONCENTRATE FORMULATIONS CONTAINING SAFLUFENACIL BASF SE (DE) 2012-11-29 — — US disclosed
US-20120271049-A1 BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES PRODUCTS FOR THEIR PREPARATION BASF AKTIENGESELLSCHAFT (DE) 2012-10-25 — — US disclosed
US-6534492-B2 Herbicidal phenylsulfamoyl carboxamides BASF AKTIENGESELLSCHAFT (DE) 2003-03-18 — — US disclosed
CN-1383425-A Uracil substituted phenyl sulfamoyl carboxamides BASF AG (DE) 2002-12-04 — — CN disclosed
CN-1383425-A Uracil substituted phenyl sulfamoyl carboxamides BASF AG (DE) 2002-12-04 — — CN disclosed
EP-1226127-A2 URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES BASF AKTIENGESELLSCHAFT (DE) 2002-07-31 — — EP disclosed
US-20020045550-A1 Uracil substituted phenyl sulfamoyl carboxamides INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) 2002-04-18 — — US disclosed
US-20020045550-A1 Uracil substituted phenyl sulfamoyl carboxamides INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) 2002-04-18 — — US disclosed
WO-2001083459-A2 URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES BASF AKTIENGESELLSCHAFT (DE) 2001-11-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045550-A1 Uracil substituted phenyl sulfamoyl carboxamides CCNH, CBR3, UNG CA1 1413/4885CA2 1329/4885KEAP1 664/4885
US-20120310010-A1 Method for producing sulfonamides MSRB3, STS, TST CA1 725/4885CA2 200/4885KEAP1 3297/4885
US-20120302444-A1 LIQUID SUSPENSION CONCENTRATE FORMULATIONS CONTAINING SAFLUFENACIL SCD5, FFAR3, FFAR2 CA1 2118/4885CA2 693/4885KEAP1 2592/4885
US-20120271049-A1 BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES PRODUCTS FOR THEIR PREPARATION TST, IDO1, TMT1A CA1 1083/4885CA2 535/4885KEAP1 177/4885
US-20030224941-A1 Uracil substituted phenyl sulfamoyl carboxamides CCNH, CBR3, UNG CA1 1413/4885CA2 1329/4885KEAP1 664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.