Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2626922 | 0.88 | HTR7 (0.63) | HTR7HTR6TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL458792 | 0.88 | HTR7 (0.63) | HTR7HTR6TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL29375465 | 0.88 | HTR7 (0.63) | HTR7HTR6TSHRL3MBTL1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL12804036 | 0.87 | HTR7 (0.62) | HTR7HTR6TSHRL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2290149 | 0.87 | HTR7 (0.65) | HTR7HTR6TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL4399057 | 0.87 | TSHR (0.72) | HTR7HTR6TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL11150077 | 0.86 | HTR7 (0.58) | HTR7HTR6TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL2296651 | 0.85 | L3MBTL1 (0.73) | HTR7HTR6L3MBTL1HTR1ADRD2 | |
| SCHEMBL5013812 | 0.85 | HTR7 (0.59) | HTR7HTR6TSHRL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2297385 | 0.85 | L3MBTL1 (0.72) | HTR7HTR6L3MBTL1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118464-A1 | HALOGENATED XANTHINE DERIVATIVES AND PRECURSORS THEREOF FOR ANTI-CANCER AND ANTI-METASTASIS ACTIVITY AND PREPARING METHOD THEREOF | KAOHSIUNG MEDICAL UNIVERSITY | 2011-05-19 | — | — | US | disclosed |
| US-20110118464-A1 | HALOGENATED XANTHINE DERIVATIVES AND PRECURSORS THEREOF FOR ANTI-CANCER AND ANTI-METASTASIS ACTIVITY AND PREPARING METHOD THEREOF | KAOHSIUNG MEDICAL UNIVERSITY | 2011-05-19 | — | — | US | disclosed |
| US-20090306093-A1 | METHOD FOR TREATING PATIENT HAVING BENIGN PROSTATE HYPERPLASIA | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118464-A1 | HALOGENATED XANTHINE DERIVATIVES AND PRECURSORS THEREOF FOR ANTI-CANCER AND ANTI-METASTASIS ACTIVITY AND PREPARING METHOD THEREOF | TK1, XDH, KYAT1 | HTR7 2141/4885HTR6 3272/4885TSHR 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.