Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 8/20 | 0.35 |
| ▸ | FGF1 | P05230 | 6/20 | 0.35 |
| ▸ | FGF2 | P09038 | 6/20 | 0.35 |
| ▸ | VEGFA | P15692 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403647 | 0.89 | CYP2D6 (0.37) | CD44CYP2D6HSD17B10THRBCA2 | |
| SCHEMBL4404462 | 0.84 | LMNA (0.42) | HPSEFGF1FGF2VEGFACYP2D6 | |
| SCHEMBL2927855 | 0.75 | CYP2D6 (0.53) | HPSEFGF1FGF2VEGFACYP2D6 | |
| SCHEMBL12920549 | 0.74 | CYP2D6 (0.52) | HPSEFGF1FGF2VEGFACYP2D6 | |
| SCHEMBL10182606 | 0.74 | ALDH1A1 (0.42) | CD44BCHECYP2D6HSD17B10THRB | |
| SCHEMBL10495764 | 0.74 | CYP2D6 (0.55) | BCHECYP2D6HSD17B10THRBCA2 | |
| SCHEMBL31252904 | 0.73 | CYP2D6 (0.57) | BCHECYP2D6HSD17B10THRBCA2 | |
| SCHEMBL5181975 | 0.73 | CYP2D6 (0.57) | BCHECYP2D6HSD17B10THRBCA2 | |
| SCHEMBL4403646 | 0.72 | SLC6A2 (0.36) | HPSEFGF1FGF2VEGFABCHE | |
| SCHEMBL17589439 | 0.72 | CYP2D6 (0.47) | HPSEFGF1FGF2VEGFACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173606-B2 | Sulfated oligosaccharide derivatives | PROGEN PHARMACEUTICALS LIMITED (AU) | 2012-05-08 | — | — | US | disclosed |
| US-20110130354-A1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PHARMACEUTICALS LIMITED (AU) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130354-A1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | HPSE, APOB, LIPG | CD44 215/4885HPSE 1/4885FGF1 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.