Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963683 | 0.89 | KMT2A (0.37) | L3MBTL1ALDH1A1LMNAPARP1PARP2 | |
| Hydrochloric Acid SCHEMBL4405691 | 0.83 | LMNA (0.37) | ALDH1A1TDP1KDM4ETSHRHTT | |
| SCHEMBL4400753 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TDP1KDM4ETSHRHTT | |
| SCHEMBL4411388 | 0.82 | CHRM2 (0.34) | ALDH1A1TDP1KDM4ETSHRHTT | |
| SCHEMBL4404600 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TDP1KDM4ETSHRHTT | |
| Hydrochloric Acid SCHEMBL4406718 | 0.81 | ALDH1A1 (0.32) | ALDH1A1TDP1KDM4ETSHRHTT | |
| Hydrochloric Acid SCHEMBL4397030 | 0.80 | DRD2 (0.35) | ALDH1A1TDP1KDM4ETSHRHTT | |
| SCHEMBL4404574 | 0.80 | ALDH1A1 (0.34) | ALDH1A1TDP1KDM4ETSHRHTT | |
| Hydrochloric Acid SCHEMBL4406706 | 0.80 | ALDH1A1 (0.34) | ALDH1A1TDP1KDM4ETSHRHTT | |
| SCHEMBL4396348 | 0.79 | SOS1 (0.34) | ALDH1A1TDP1TSHRHTTSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |