Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.75 |
| ▸ | DRD3 | P35462 | 2/20 | 0.71 |
| ▸ | HTR1A | P08908 | 4/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9132672 | 0.98 | DRD2 (0.73) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL2215388 | 0.91 | DRD2 (0.76) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL29395171 | 0.91 | DRD2 (0.76) | DRD2DRD3HTR1AADRA1DADRA1A | |
| Propylamine SCHEMBL28972784 | 0.90 | DRD2 (0.89) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL30080718 | 0.90 | HTR1A (0.77) | DRD2DRD3HTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL11047866 | 0.90 | DRD2 (0.74) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL946736 | 0.90 | HTR1A (0.77) | DRD2DRD3HTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL29072812 | 0.90 | DRD2 (0.74) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL30080722 | 0.90 | HTR1A (0.77) | DRD2DRD3HTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL3196123 | 0.88 | HTR1A (0.75) | DRD2DRD3HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971600-B1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-08-21 | — | — | EP | claimed |
| US-20090131336-A1 | Isoxazole Derivatives and Use Thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2009-05-21 | — | — | US | claimed |
| EP-0539180-A1 | Antiviral agents | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-04-28 | — | — | EP | claimed |
| JP-11092458-A | — | — | None | — | — | JP | disclosed |
| JP-10114755-A | — | — | None | — | — | JP | disclosed |
| JP-60169470-A | — | — | None | — | — | JP | disclosed |
| CN-111253325-A | Amino quinazoline aryl piperazine compound and pharmaceutical composition and application thereof | 广州大学 | 2020-06-09 | — | — | CN | disclosed |
| EP-1971600-B1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-08-21 | — | — | EP | disclosed |
| US-20090131336-A1 | Isoxazole Derivatives and Use Thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2009-05-21 | — | — | US | disclosed |
| EP-0906100-B1 | USE OF 5-HT 1A? RECEPTOR ANTAGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE | RECORDATI CHEM PHARM (CH) | 2004-01-28 | — | — | EP | disclosed |
| EP-1000047-B1 | 1-(N-PHENYLAMINOALKYL)-PIPERAZINE DERIVATIVES SUBSTITUTED AT POSITION 2 OF THE PHENYL RING | RECORDATI CHEM PHARM (CH) | 2003-12-17 | — | — | EP | disclosed |
| JP-S60169470-A | NOVEL PHENYLPIPERAZINE DERIVATIVE | CHUGAI PHARMACEUT CO LTD | 1985-09-02 | — | — | JP | disclosed |
| WO-1984004302-A1 | SUBSTITUTED PICOLINIC ACIDS, PROCESSES FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1984-11-08 | — | — | WO | disclosed |
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |
| EP-0089065-A2 | Novel phenylpiperazine derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1983-09-21 | — | — | EP | disclosed |
| EP-0000220-B1 | DIHYDROURACILS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-04-29 | — | — | EP | disclosed |
| US-4216216-A | TREATING MIGRAINE HEADACHES, ANTI-HISTAMINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |
| EP-0000220-A1 | Dihydrouracils, process for their preparation and pharmaceuticals containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |
| US-3966950-A | ALPHA-ADRENOLYTIC ACTIVITY | ROUSSEL-UCLAF (FR) | 1976-06-29 | — | — | US | disclosed |
| US-3948898-A | HYPOTENSIVES, SEDATIVES, ANTIARRHYTHMICS, BRADYCARDIACS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131336-A1 | Isoxazole Derivatives and Use Thereof | WNT3A, WNT1, WNT3 | DRD2 3882/4885DRD3 3114/4885HTR1A 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.