SCHEMBL4404459

SCHEMBL4404459

CCC1O[C@H](OCc2ccccc2)C(O)[C@@H](C)[C@@H]1C

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.40
SLC5A2 P31639 2/20 0.40
SSTR5 P35346 2/20 0.38
FGF1 P05230 2/20 0.37
FGF2 P09038 2/20 0.37
VEGFA P15692 2/20 0.37
HPSE Q9Y251 2/20 0.37
LGALS8 O00214 1/20 0.37
PDE4D Q08499 1/20 0.36
SSTR1 P30872 1/20 0.36
SSTR2 P30874 1/20 0.36
SSTR4 P31391 1/20 0.36
SSTR3 P32745 1/20 0.36
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9925406 0.89 SLC6A2 (0.46) SLC6A2SLC5A2SSTR5FGF1FGF2
SCHEMBL16640651 0.89 SLC6A2 (0.40) SLC6A2SLC5A2SSTR5FGF1FGF2
SCHEMBL18718066 0.89 SLC6A2 (0.48) SLC6A2SLC5A2LGALS8PDE4D
SCHEMBL15280895 0.87 FGF1 (0.39) SLC6A2SSTR5FGF1FGF2VEGFA
SCHEMBL18653425 0.86 SLC6A2 (0.44) SLC6A2SSTR5FGF1FGF2VEGFA
SCHEMBL15504371 0.85 SLC5A2 (0.47) SLC6A2SLC5A2
SCHEMBL14903581 0.85 SLC5A2 (0.47) SLC6A2SLC5A2
SCHEMBL14903579 0.85 SLC5A2 (0.47) SLC6A2SLC5A2
SCHEMBL15504369 0.84 FGF1 (0.43) SLC6A2SSTR5FGF1FGF2VEGFA
SCHEMBL18328600 0.84 FGF1 (0.43) SLC6A2SSTR5FGF1FGF2VEGFA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173606-B2 Sulfated oligosaccharide derivatives PROGEN PHARMACEUTICALS LIMITED (AU) 2012-05-08 US disclosed
US-20110130354-A1 SULFATED OLIGOSACCHARIDE DERIVATIVES PROGEN PHARMACEUTICALS LIMITED (AU) 2011-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130354-A1 SULFATED OLIGOSACCHARIDE DERIVATIVES HPSE, APOB, LIPG SLC6A2 4286/4885SLC5A2 799/4885SSTR5 2504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.