Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409298 | 0.93 | MCHR1 (0.35) | MCHR1KCNH2 | |
| SCHEMBL4394210 | 0.92 | MCHR1 (0.34) | MAOBALDH1A1MCHR1KCNH2SLC2A1 | |
| SCHEMBL4396436 | 0.92 | DRD2 (0.33) | MAOBADRB2ADRB1ADRB3ACHE | |
| SCHEMBL4399337 | 0.92 | MAOB (0.41) | MAOBALDH1A1MCHR1KCNH2LTA4H | |
| SCHEMBL4398647 | 0.91 | KDM4E (0.33) | MAOBALDH1A1MCHR1ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL4412704 | 0.90 | HTR1A (0.31) | — | |
| SCHEMBL914530 | 0.90 | MAOB (0.41) | MAOBALDH1A1MCHR1KCNH2LTA4H | |
| SCHEMBL4410335 | 0.90 | MCHR1 (0.33) | ALDH1A1MCHR1SLC2A1ADRB2ADRB1 | |
| SCHEMBL4396633 | 0.89 | SOS1 (0.34) | MAOBMCHR1KCNH2ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL4541892 | 0.88 | SOS1 (0.33) | MAOBALDH1A1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |