Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409008 | 0.87 | LMNA (0.49) | LMNAHSD17B10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL4405748 | 0.79 | LMNA (0.53) | LMNAHSD17B10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL2012054 | 0.79 | LMNA (0.53) | LMNAHSD17B10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL4408728 | 0.79 | ALDH1A1 (0.50) | LMNAHSD17B10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL976147 | 0.78 | LMNA (0.47) | LMNAHSD17B10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL4407811 | 0.76 | LMNA (0.50) | LMNAHSD17B10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL8947286 | 0.74 | PTGS2 (0.46) | LMNAHSD17B10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL4403766 | 0.72 | ALDH1A1 (0.50) | LMNAHSD17B10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL10737969 | 0.71 | HSD17B10 (0.42) | LMNAHSD17B10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL890039 | 0.71 | LMNA (0.77) | LMNAHSD17B10ALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |