Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL351809 | 0.98 | LMNA (0.74) | LMNAHSD17B10ALDH1A1L3MBTL1PTGS2 | |
| Bromide SCHEMBL28098177 | 0.98 | LMNA (0.74) | LMNAHSD17B10ALDH1A1L3MBTL1PTGS2 | |
| Hydrochloric Acid SCHEMBL7981337 | 0.98 | LMNA (0.74) | LMNAHSD17B10ALDH1A1L3MBTL1PTGS2 | |
| SCHEMBL11531369 | 0.90 | ALDH1A1 (0.70) | LMNAHSD17B10ALDH1A1L3MBTL1PTGS2 | |
| Urea SCHEMBL28915393 | 0.89 | PTGS2 (0.64) | LMNAHSD17B10ALDH1A1L3MBTL1PTGS2 | |
| SCHEMBL11536760 | 0.89 | ALDH1A1 (0.65) | LMNAHSD17B10ALDH1A1L3MBTL1PTGS2 | |
| SCHEMBL15452507 | 0.89 | ALDH1A1 (0.71) | LMNAHSD17B10ALDH1A1L3MBTL1PTGS2 | |
| SCHEMBL8534360 | 0.87 | LMNA (0.71) | LMNAHSD17B10ALDH1A1L3MBTL1PTGS2 | |
| Hydrochloric Acid SCHEMBL5459649 | 0.87 | L3MBTL1 (0.73) | LMNAHSD17B10ALDH1A1L3MBTL1PTGS2 | |
| SCHEMBL15541266 | 0.86 | ALDH1A1 (0.63) | LMNAHSD17B10ALDH1A1L3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814702-B | Curable organosilicon composition and optical semiconductor device | 道康宁东丽株式会社 | 2018-06-26 | — | — | CN | claimed |
| US-9691951-B2 | Curable silicone composition, and optical semiconductor device | DOW CORNING TORAY CO., LTD. (JP) | 2017-06-27 | — | — | US | claimed |
| CN-106749070-A | New Biphenyltetrazoles derivative and preparation method thereof | 北方民族大学 | 2017-05-31 | — | — | CN | claimed |
| EP-3059768-A1 | CURABLE SILICONE COMPOSITION, AND OPTICAL SEMICONDUCTOR DEVICE | Dow Corning Toray Co., Ltd. (JP) | 2016-08-24 | — | — | EP | claimed |
| US-20160233395-A1 | Curable Silicone Composition, And Optical Semiconductor Device | DOW TORAY CO., LTD. (JP) | 2016-08-11 | — | — | US | claimed |
| CN-101143853-B | Biphenyltetrazoles compounds and preparation method thereof | UNIV SHENYANG PHARMACEUTICAL | 2012-05-16 | — | — | CN | claimed |
| EP-2001869-A1 | PROCESS FOR PRODUCING BIPHENYL-TETRAZOLE COMPOUNDS | Ulkar Kimya Sanayii Ve Ticaret A.S. (TR) | 2008-12-17 | — | — | EP | claimed |
| CN-101143853-A | Biphenyltetrazoles compounds and preparation method thereof | UNIV SHENYANG PHARMACEUTICAL (CN) | 2008-03-19 | — | — | CN | claimed |
| WO-2008018843-A1 | PROCESS FOR PRODUCING USEFUL SALTS FORM OF BIPHENYL-TETRAZOLE COMPOUNDS | ULKAR KIMYA SANAYI VE TICARET AS (TR) | 2008-02-14 | — | — | WO | claimed |
| EP-0720657-B1 | BIOLOGICALLY RELEVANT METHODS FOR THE RAPID DETERMINATION OF STERILITY | 3M INNOVATIVE PROPERTIES CO (US) | 2007-08-15 | — | — | EP | claimed |
| WO-2006097121-A1 | METHOD FOR PRODUCING BIPHENYL-TETRAZOLE COMPOUNDS | ULKAR KIMYA SANAYII VE TICARET A.S. (TR) | 2006-09-21 | — | — | WO | claimed |
| WO-2006098705-A1 | PROCESS FOR PRODUCING BIPHENYL-TETRAZOLE COMPOUNDS | ULKAR KIMYA SANAYII VE TICARET AS (TR) | 2006-09-21 | — | — | WO | claimed |
| US-20050059720-A1 | Medicinal compositions for the prevention or treatment of cardiac failure | SANKYO COMPANY, LIMITED (JP) | 2005-03-17 | — | — | US | claimed |
| US-20030181500-A1 | Medicinal compositions for the prevention or treatment of cardiac failure | SANKYO COMPANY, LIMITED (JP) | 2003-09-25 | — | — | US | claimed |
| EP-0734398-B1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2002-02-27 | — | — | EP | claimed |
| EP-0842424-B1 | PROCESS FOR DETERMINING THE EFFECTIVENESS AND TOLERANCE OF A XENOGENIC SUBSTANCE ADMINISTERED TO AN ORGANISM | LAUK CHRISTIANE (DE) | 1999-11-03 | — | — | EP | claimed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | claimed |
| JP-10081632-A | — | — | None | — | — | JP | disclosed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059720-A1 | Medicinal compositions for the prevention or treatment of cardiac failure | HMGCR, AGTR2, ACE | LMNA 702/4885HSD17B10 1340/4885ALDH1A1 4144/4885 |
| US-20030181500-A1 | Medicinal compositions for the prevention or treatment of cardiac failure | HMGCR, AGTR2, ACE | LMNA 702/4885HSD17B10 1340/4885ALDH1A1 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.