Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 9/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL4407325 | 1.00 | NLRP3 (0.44) | NLRP3CACNA1BPOLBKDM4EMMP1 | |
| SCHEMBL4955341 | 0.96 | NLRP3 (0.47) | NLRP3CACNA1BPOLBKDM4EMMP1 | |
| SCHEMBL4404890 | 0.78 | TRPM2 (0.49) | POLBKDM4EMMP1MMP2MMP9 | |
| SCHEMBL4404884 | 0.78 | TRPM2 (0.49) | POLBKDM4EMMP1MMP2MMP9 | |
| SCHEMBL1095326 | 0.77 | NLRP3 (0.61) | NLRP3POLBKDM4EALDH1A1RAB9A | |
| SCHEMBL9147553 | 0.76 | SMN1; SMN2 (0.50) | CACNA1BKDM4EMMP1MMP2MMP9 | |
| SCHEMBL9147560 | 0.76 | SMN1; SMN2 (0.50) | CACNA1BKDM4EMMP1MMP2MMP9 | |
| SCHEMBL6929631 | 0.75 | NPC1 (0.63) | NLRP3POLBKDM4EALDH1A1RAB9A | |
| SCHEMBL9512860 | 0.73 | CACNA1B (0.52) | CACNA1BMMP1MMP2MMP9MMP12 | |
| SCHEMBL4955339 | 0.72 | L3MBTL1 (0.57) | POLBKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664049-B1 | SYNTHESIS OF PROTECTED PYRROLOBENZODIAZEPINES | SPIROGEN LTD (GB) | 2009-12-23 | — | — | EP | disclosed |