SCHEMBL6279031

SCHEMBL6279031

C=CCc1ccc(NC(=O)C=C)cc1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 15/20 0.59
F13A1 P00488 4/20 0.59
TGM1 P22735 4/20 0.59
LMNA P02545 1/20 0.59
TGM3 Q08188 1/20 0.59
THRA P10827 1/20 0.58
THRB P10828 1/20 0.58
FGFR1 P11362 1/20 0.45
FGFR4 P22455 1/20 0.45
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25293287 0.89 TGM2 (0.59) TGM2F13A1TGM1LMNATGM3
SCHEMBL10503744 0.87 THRB (0.49) TGM2F13A1TGM1LMNATGM3
SCHEMBL440756 0.85 TGM2 (0.63) TGM2F13A1TGM1LMNATGM3
SCHEMBL439369 0.84 TGM2 (0.79) TGM2F13A1TGM1LMNATGM3
SCHEMBL1191835 0.83 TGM2 (0.61) TGM2F13A1TGM1LMNATGM3
SCHEMBL11134234 0.83 TGM2 (0.43) TGM2F13A1TGM1LMNATGM3
SCHEMBL16242100 0.83 TGM2 (0.61) TGM2F13A1TGM1LMNATGM3
SCHEMBL7916277 0.81 SMN1; SMN2 (0.53) LMNACYP1A2HSD17B10
SCHEMBL7754428 0.81 PEPD (0.52) LMNATHRATHRBCYP1A2CYP2D6
SCHEMBL1497339 0.81 TGM2 (0.59) TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890625-B2 Aqueous adhesive WACKER CHEMICAL CORP (US) 2014-05-21 EP disclosed
EP-0890625-B1 Aqueous adhesive AIR PROD & CHEM (US) 2005-11-23 EP disclosed
EP-1411097-A1 Water-based adhesive compositions using waterborne polyesters AIR PRODUCTS POLYMERS, L.P. (US) 2004-04-21 EP disclosed
US-20040072003-A1 Water-based adhesive compositions using waterborne polyesters AIR PRODUCTS POLYMERS, L.P. 2004-04-15 US disclosed
US-6063858-A COMPRISING ETHYLENE-VINYL ACETATE COPOLYMER STABILIZED BY POLYVILYL ALCOHOL AND A CAST FILM; PLASTICS PACKAGING MATERIALS AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-05-16 US disclosed
US-5872181-A AN ADHESIVE COMPRISES VINYL ACETATE-ETHYLENE COPOLYMER OR TERPOLYMER WITH ETHYLENICALLY UNSATURATED COPOLYMERIZABLE MONOMER, CAST FILM OF ADHESIVE HAVE PREFERENTIAL TENSILE STORAGE MODULUS AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-02-16 US disclosed
EP-0890625-A1 Aqueous adhesive AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-01-13 EP disclosed
US-5500251-A (METH)ACRYLAMIDES AND MALEIMIDES AIR PRODUCTS AND CHEMICALS, INC. (US) 1996-03-19 US disclosed
US-5500251-A (METH)ACRYLAMIDES AND MALEIMIDES AIR PRODUCTS AND CHEMICALS, INC. (US) 1996-03-19 US disclosed