SCHEMBL4408017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14293610	0.94	KDM4E (0.69)	KDM4EALOX15NOS1MPOKMT2A
	SCHEMBL4413889	0.89	KDM4E (0.56)	KDM4EALOX15MPOKMT2ACHRM2
	SCHEMBL4404501	0.87	KDM4E (0.55)	KDM4EALOX15NOS1KMT2ANOS3
	SCHEMBL4404341	0.85	KDM4E (0.50)	KDM4EALOX15KMT2ACHRM2ALDH1A1
	SCHEMBL4413514	0.85	KDM4E (0.50)	KDM4EALOX15KMT2ACHRM2ALDH1A1
	SCHEMBL4404505	0.84	CHRM2 (0.53)	KDM4EALOX15KMT2ACHRM2ALDH1A1
	SCHEMBL4409049	0.84	KDM4E (0.51)	KDM4EALOX15KMT2ACHRM2ALDH1A1
	SCHEMBL14293672	0.83	KDM4E (0.52)	KDM4EALOX15MPOKMT2ACHRM2
	SCHEMBL14293606	0.82	KDM4E (0.52)	KDM4EALOX15NOS1KMT2ANOS3
	SCHEMBL4409089	0.82	CHRM2 (0.57)	KDM4EALOX15KMT2ACHRM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.