Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754547 | 0.77 | ALDH1A1 (0.52) | ALDH1A1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL986289 | 0.77 | HDAC6 (0.43) | ALDH1A1GAACES2CES1NPC1 | |
| SCHEMBL15153061 | 0.73 | NPC1 (0.41) | ALDH1A1GAACES2CES1NPC1 | |
| SCHEMBL30975214 | 0.72 | ALDH1A1 (0.58) | ALDH1A1GAAOPRD1KCNH2CES2 | |
| SCHEMBL8405203 | 0.72 | ALDH1A1 (0.58) | ALDH1A1GAAOPRD1KCNH2CES2 | |
| SCHEMBL16741186 | 0.70 | ALDH1A1 (0.53) | ALDH1A1GAAOPRD1KCNH2CES2 | |
| SCHEMBL746435 | 0.70 | MLYCD (0.39) | ALDH1A1GAAOPRD1TP53HPGD | |
| SCHEMBL10416948 | 0.70 | GRM1 (0.45) | ALDH1A1GAAOPRD1KCNH2CES2 | |
| Hydrochloric Acid SCHEMBL30476602 | 0.69 | ALDH1A1 (0.52) | ALDH1A1GAAOPRD1KCNH2CES2 | |
| SCHEMBL30975242 | 0.67 | KDM4E (0.52) | ALDH1A1GAAOPRD1KCNH2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042905-A1 | TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | AETERNA ZENTARIS GMBH (DE) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042905-A1 | TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | GPR3, GRK3, GPR88 | ALDH1A1 2149/4885GAA 3696/4885OPRD1 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.