Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001626 | 0.74 | ADRA2C (0.65) | MLYCDADRA2CHTTALDH1A1HPGD | |
| SCHEMBL20985601 | 0.72 | HTT (0.40) | HTTALDH1A1TP53TSHR | |
| SCHEMBL4408034 | 0.70 | ALDH1A1 (0.41) | GRM1HTTALDH1A1HPGDTP53 | |
| SCHEMBL986589 | 0.69 | TSHR (0.47) | HTTALDH1A1TP53TSHR | |
| SCHEMBL1003735 | 0.68 | TP53 (0.68) | MLYCDHDAC1HDAC6ALDH1A1HPGD | |
| SCHEMBL13571678 | 0.68 | TP53 (0.52) | MLYCDHDAC1HDAC6ADRA2CALDH1A1 | |
| SCHEMBL28997857 | 0.67 | ADRA2C (0.51) | ADRA2CHTTALDH1A1HPGDTP53 | |
| SCHEMBL1006489 | 0.67 | NAMPT (0.54) | MLYCDHDAC1HDAC6ALDH1A1HPGD | |
| SCHEMBL28592135 | 0.67 | HPGD (0.50) | HDAC1HDAC6ALDH1A1HPGDTP53 | |
| SCHEMBL1928093 | 0.66 | PKM (0.54) | MLYCDADRA2CHTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138356-B2 | Chemical inhibitors of inhibitors of differentiation | Angiogeney, Inc. (US) | 2012-03-20 | — | — | US | disclosed |