Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 3/20 | 0.30 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408031 | 0.80 | CCNC (0.32) | CCNCCDK8BRAFXDH | |
| SCHEMBL986290 | 0.75 | DYRK1B (0.39) | CCNCCDK8IKBKBCSNK1A1TYRO3 | |
| SCHEMBL8598306 | 0.73 | NOS3 (0.39) | CCNCCDK8IKBKBBRAFUSP7 | |
| SCHEMBL986288 | 0.72 | FYN (0.38) | CDK8IKBKBCHUKCSNK1A1TYRO3 | |
| SCHEMBL15153064 | 0.72 | CHEK2 (0.36) | CSNK1A1TYRO3DYRK1BNUDT1BRAF | |
| SCHEMBL19439176 | 0.71 | CCNC (0.41) | CCNCCDK8NOS3NOS2 | |
| SCHEMBL20579525 | 0.71 | NOS2 (0.42) | CCNCCDK8IKBKBBRAFUSP7 | |
| SCHEMBL946827 | 0.71 | MKNK1 (0.47) | IKBKBNUDT1 | |
| SCHEMBL946838 | 0.71 | MKNK1 (0.38) | CCNCCDK8NUDT1 | |
| SCHEMBL746436 | 0.71 | CSNK1A1 (0.38) | CSNK1A1TYRO3DYRK1BNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042905-A1 | TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | AETERNA ZENTARIS GMBH (DE) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042905-A1 | TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | GPR3, GRK3, GPR88 | CCNC 4123/4885CDK8 1535/4885IKBKB 3355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.