SCHEMBL4408477

SCHEMBL4408477

CCN(CC)c1ccc(S(N)(=O)=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
CA2 P00918 11/20 0.59
CA1 P00915 8/20 0.59
CA9 Q16790 8/20 0.59
CA12 O43570 6/20 0.59
CA7 P43166 4/20 0.59
CA4 P22748 1/20 0.59
L3MBTL1 Q9Y468 3/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
MAPT P10636 2/20 0.55
HPGD P15428 2/20 0.55
PSMD14 O00487 1/20 0.54
CYP3A4 P08684 1/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
RECQL P46063 1/20 0.54
GFER P55789 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
CNR2 P34972 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8666349 0.89 CA12 (0.68) ALDH1A1CA2CA1CA9CA12
SCHEMBL15124998 0.89 CA12 (0.68) ALDH1A1CA2CA1CA9CA12
SCHEMBL414561 0.84 CA2 (0.56) ALDH1A1CA2CA1CA9CA12
SCHEMBL6313828 0.83 ALDH1A1 (0.58) ALDH1A1L3MBTL1MEN1KMT2AMAPT
SCHEMBL28417720 0.82 CA2 (0.62) CA2CA1CA9CA12CA7
SCHEMBL3229040 0.79 ALDH1A1 (0.65) ALDH1A1L3MBTL1MEN1KMT2AMAPT
SCHEMBL3223255 0.79 ALDH1A1 (0.55) ALDH1A1L3MBTL1MEN1KMT2AMAPT
Methanesulfonamide SCHEMBL10655700 0.78 ALDH1A1 (0.76) ALDH1A1L3MBTL1MEN1KMT2AMAPT
Benzenesulfonamide SCHEMBL9749746 0.77 HSD11B1 (0.54) ALDH1A1CA2CA1CA9CA12
SCHEMBL18995911 0.77 CA2 (0.49) CA2CA1CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960081-A Endoplasmic reticulum targeted glutathione fluorescent probe and preparation method thereof 青岛科技大学 2023-04-14 CN claimed
CN-115960081-A Endoplasmic reticulum targeted glutathione fluorescent probe and preparation method thereof 青岛科技大学 2023-04-14 CN disclosed
US-7635662-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2009-12-22 US disclosed
US-20010044553-A1 Novel compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2001-11-22 US disclosed
US-5565494-A BENZENESULFONYLUREA DERIVATIVES ELI LILLY AND COMPANY (US) 1996-10-15 US disclosed
EP-0602878-A1 Diarylsulfonylureas and their use as antitumor agents ELI LILLY AND COMPANY (US) 1994-06-22 EP disclosed
US-4515963-A AMIDATIUON OF NAPHTHOLACTONE CIBA GEIGY AG (CH) 1985-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010044553-A1 Novel compound for color-producing composition, and recording material UROD, UMPS, UGT1A10 ALDH1A1 99/4885CA2 1209/4885CA1 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.