Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408776 | 0.79 | ALDH1A1 (0.60) | MAPK1HRH3HRH4SLC1A3SLC1A2 | |
| SCHEMBL10969069 | 0.78 | ALDH1A1 (0.59) | MAPK1HRH3HRH4SLC1A3SLC1A2 | |
| SCHEMBL4522517 | 0.75 | HRH3 (0.51) | MAPK1HRH3HRH4SLC1A2ALDH1A1 | |
| SCHEMBL27333607 | 0.73 | LMNA (0.57) | MAPK1ALDH1A1TSHRPKMLMNA | |
| SCHEMBL18387989 | 0.73 | ALDH1A1 (0.57) | MAPK1HRH3HRH4SLC1A3SLC1A2 | |
| SCHEMBL29761986 | 0.72 | SLC1A2 (0.89) | MAPK1HRH3HRH4SLC1A3SLC1A2 | |
| SCHEMBL14605917 | 0.71 | ALDH1A1 (0.55) | MAPK1HRH3HRH4HDAC1HDAC6 | |
| SCHEMBL4408444 | 0.71 | LMNA (0.59) | MAPK1ALDH1A1TSHRLMNA | |
| SCHEMBL2163180 | 0.71 | LMNA (0.59) | ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL96820 | 0.70 | ALDH1A1 (0.57) | MAPK1HDAC1HDAC6ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306397-A1 | Method for the production of substituted azoles | LANXESS DEUTSCHLAND GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-1891025-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED AZOLES | Lanxess Deutschland GmbH (DE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006131228-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED AZOLES | LANXESS DEUTSCHLAND GMBH (DE) | 2006-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306397-A1 | Method for the production of substituted azoles | CYP11B1, CYP11B2, CYP4F11 | MAPK1 1799/4885HRH3 926/4885HRH4 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.