Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314086 | 1.00 | PAX8 (0.48) | PAX8ALDH1A1TSHRHRH3MAPK1 | |
| SCHEMBL1414083 | 0.75 | GHSR (0.53) | ALDH1A1TSHRHRH3MAPK1HRH4 | |
| SCHEMBL1414080 | 0.75 | GHSR (0.53) | ALDH1A1TSHRHRH3MAPK1HRH4 | |
| SCHEMBL4408776 | 0.75 | ALDH1A1 (0.60) | ALDH1A1TSHRHRH3MAPK1HRH4 | |
| Hydrochloric Acid SCHEMBL27173732 | 0.75 | TSHR (0.43) | ALDH1A1TSHRHRH3MAPK1HRH4 | |
| SCHEMBL10969069 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TSHRHRH3MAPK1HRH4 | |
| SCHEMBL7309451 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRNPSR1LMNAMAPT | |
| SCHEMBL7309462 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRNPSR1LMNAMAPT | |
| SCHEMBL18387989 | 0.70 | ALDH1A1 (0.57) | ALDH1A1TSHRHRH3MAPK1HRH4 | |
| SCHEMBL4518149 | 0.69 | MAPK1 (0.56) | ALDH1A1TSHRHRH3MAPK1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |