SCHEMBL4409916

SCHEMBL4409916

COO[C@@H]1C(OC(=O)c2ccccc2)[C@@H](O[C@@H]2C(OC(=O)c3ccccc3)COC(COC(=O)c3ccccc3)[C@H]2C)OC(COC(=O)c2ccccc2)[C@H]1C

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 4/20 0.38
▸ BCHE P06276 4/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ USP2 O75604 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.36
▸ F11 P03951 1/20 0.36
▸ ANTXR2 P58335 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4404804 0.91 BCHE (0.41) PTPN1BCHEMEN1USP2POLB
SCHEMBL4402919 0.89 PTPN1 (0.38) PTPN1BCHEMEN1USP2POLB
SCHEMBL4403646 0.83 SLC6A2 (0.36) PTPN1BCHEANTXR2
SCHEMBL17612542 0.78 ANTXR2 (0.53) PTPN1MEN1USP2POLBKMT2A
SCHEMBL4292941 0.78 PTPN1 (0.48) PTPN1MEN1USP2POLBKMT2A
SCHEMBL23348434 0.78 BCHE (0.49) PTPN1BCHEMEN1USP2POLB
SCHEMBL14208566 0.78 BCHE (0.49) PTPN1BCHEMEN1USP2POLB
SCHEMBL14413573 0.78 BCHE (0.49) PTPN1BCHEMEN1USP2POLB
SCHEMBL21886718 0.78 BCHE (0.49) PTPN1BCHEMEN1USP2POLB
SCHEMBL19944547 0.78 BCHE (0.49) PTPN1BCHEMEN1USP2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173606-B2 Sulfated oligosaccharide derivatives PROGEN PHARMACEUTICALS LIMITED (AU) 2012-05-08 — — US disclosed
US-20110130354-A1 SULFATED OLIGOSACCHARIDE DERIVATIVES PROGEN PHARMACEUTICALS LIMITED (AU) 2011-06-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130354-A1 SULFATED OLIGOSACCHARIDE DERIVATIVES HPSE, APOB, LIPG PTPN1 612/4885BCHE 2364/4885MEN1 4646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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