SCHEMBL4404804

SCHEMBL4404804

C[C@@H]1C(COC(=O)c2ccccc2)O[C@H](O[C@@H]2C(OC(=O)c3ccccc3)[C@@H](O[C@@H]3C(OC(=O)c4ccccc4)COC(COC(=O)c4ccccc4)[C@H]3C)OC(COC(=O)c3ccccc3)[C@H]2C)C(OC(=O)c2ccccc2)[C@H]1C

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 4/20 0.41
▸ PTPN1 P18031 3/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ USP2 O75604 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.37
▸ F11 P03951 1/20 0.37
▸ ANTXR2 P58335 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4402919 0.93 PTPN1 (0.38) BCHEPTPN1MEN1USP2POLB
SCHEMBL4409916 0.91 PTPN1 (0.38) BCHEPTPN1MEN1USP2POLB
SCHEMBL4403646 0.87 SLC6A2 (0.36) BCHEPTPN1ANTXR2
SCHEMBL19036055 0.82 PTPN1 (0.50) PTPN1MEN1USP2POLBKMT2A
SCHEMBL18067737 0.81 PTPN1 (0.53) PTPN1MEN1USP2POLBKMT2A
SCHEMBL12292268 0.81 PTPN1 (0.53) PTPN1MEN1USP2POLBKMT2A
SCHEMBL11981201 0.81 PTPN1 (0.53) PTPN1MEN1USP2POLBKMT2A
SCHEMBL18067749 0.80 ALDH1A1 (0.40) BCHEPTPN1MEN1USP2POLB
SCHEMBL18067736 0.80 ALDH1A1 (0.40) BCHEPTPN1MEN1USP2POLB
SCHEMBL27408610 0.80 PAX8 (0.40) PTPN1MEN1USP2POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173606-B2 Sulfated oligosaccharide derivatives PROGEN PHARMACEUTICALS LIMITED (AU) 2012-05-08 — — US disclosed
US-20110130354-A1 SULFATED OLIGOSACCHARIDE DERIVATIVES PROGEN PHARMACEUTICALS LIMITED (AU) 2011-06-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130354-A1 SULFATED OLIGOSACCHARIDE DERIVATIVES HPSE, APOB, LIPG BCHE 2364/4885PTPN1 612/4885MEN1 4646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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