Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.49 |
| ▸ | MMP13 | P45452 | 11/20 | 0.49 |
| ▸ | MMP1 | P03956 | 11/20 | 0.49 |
| ▸ | MMP3 | P08254 | 10/20 | 0.49 |
| ▸ | MMP9 | P14780 | 10/20 | 0.49 |
| ▸ | MMP7 | P09237 | 8/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417958 | 0.87 | ALDH1A1 (0.47) | MMP2MMP13MMP9CTSLCTSS | |
| SCHEMBL4414191 | 0.86 | MMP2 (0.48) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL4414186 | 0.86 | MMP2 (0.48) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL8445738 | 0.83 | CTSL (0.67) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL8445730 | 0.81 | MMP2 (0.59) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL8283236 | 0.79 | MMP2 (0.61) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL3615326 | 0.79 | MMP2 (0.61) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL1656896 | 0.79 | MMP2 (0.61) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL7763738 | 0.76 | MMP2 (0.68) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL7867746 | 0.76 | MMP2 (0.68) | MMP2MMP13MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313737-B1 | NOVEL GUANIDINO DERIVATIVES AS INHIBITORS OF CELL ADHESION | AVENTIS PHARMA GMBH (DE) | 2009-06-03 | — | — | EP | disclosed |
| US-7259159-B2 | Guanidino derivatives as inhibitors of cell adhesion | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-08-21 | — | — | US | disclosed |
| US-20030203896-A1 | Novel guanidino derivatives as inhibitors of cell adhesion | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-10-30 | — | — | US | disclosed |
| EP-1313737-A1 | NOVEL GUANIDINO DERIVATIVES AS INHIBITORS OF CELL ADHESION | Aventis Pharma Deutschland GmbH (DE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002010168-A1 | NOVEL GUANIDINO DERIVATIVES AS INHIBITORS OF CELL ADHESION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-02-07 | — | — | WO | disclosed |
| EP-1176145-A1 | Novel guanidino derivatives as inhibitors of cell adhesion | Aventis Pharma Deutschland GmbH (DE) | 2002-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203896-A1 | Novel guanidino derivatives as inhibitors of cell adhesion | ADGRF1, VCAM1, ADGRE5 | MMP2 555/4885MMP13 549/4885MMP1 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.