Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.59 |
| ▸ | MMP1 | P03956 | 8/20 | 0.59 |
| ▸ | MMP13 | P45452 | 8/20 | 0.59 |
| ▸ | MMP9 | P14780 | 7/20 | 0.59 |
| ▸ | MMP3 | P08254 | 7/20 | 0.59 |
| ▸ | MMP7 | P09237 | 6/20 | 0.59 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3615326 | 0.86 | MMP2 (0.61) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL8283236 | 0.86 | MMP2 (0.61) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL1656896 | 0.86 | MMP2 (0.61) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL1185524 | 0.86 | MMP2 (0.50) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL27465878 | 0.86 | ALDH1A1 (0.50) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL1186251 | 0.86 | MMP2 (0.50) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL789823 | 0.85 | ADAMTS4 (0.54) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL29540524 | 0.84 | HSD17B10 (0.54) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL7897307 | 0.84 | ADAMTS4 (0.47) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL7763738 | 0.83 | MMP2 (0.68) | MMP2MMP1MMP13MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |