Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL10584446 | 0.90 | GPR84 (0.52) | GPR84FFAR1USP2PLA2G2CKDM4E | |
| SCHEMBL11922960 | 0.90 | GPR84 (0.59) | GPR84FFAR1NAAA | |
| SCHEMBL8375622 | 0.90 | GPR84 (0.59) | GPR84FFAR1NAAA | |
| SCHEMBL151961 | 0.90 | GPR84 (0.59) | GPR84FFAR1NAAA | |
| SCHEMBL17373195 | 0.90 | GPR84 (0.59) | GPR84FFAR1NAAA | |
| SCHEMBL8981942 | 0.90 | GPR84 (0.59) | GPR84FFAR1NAAA | |
| SCHEMBL13634116 | 0.90 | GPR84 (0.59) | GPR84FFAR1NAAA | |
| SCHEMBL6864319 | 0.90 | GPR84 (0.59) | GPR84FFAR1NAAA | |
| SCHEMBL8376969 | 0.90 | GPR84 (0.59) | GPR84FFAR1NAAA | |
| SCHEMBL13002969 | 0.90 | GPR84 (0.59) | GPR84FFAR1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031781-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | GENZYME CORPORATION (US) | 2016-02-04 | — | — | US | disclosed |
| US-20120064147-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | GENZYME CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |
| US-20090312440-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSHAFTEN E.V. (DE) | 2009-12-17 | — | — | US | disclosed |
| US-20040146535-A1 | Agent for improving tissue penetration | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSHAFTEN E.V. (DE) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040146535-A1 | Agent for improving tissue penetration | PGF, MMP8, MMP1 | GPR84 588/4885FFAR1 2260/4885USP2 3018/4885 |
| US-20090312440-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | PGF, MMP8, MMP1 | GPR84 588/4885FFAR1 2260/4885USP2 3018/4885 |
| US-20160031781-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | PGF, MMP8, MMP1 | GPR84 588/4885FFAR1 2260/4885USP2 3018/4885 |
| US-20120064147-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | PGF, MMP8, MMP1 | GPR84 588/4885FFAR1 2260/4885USP2 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.