Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.78 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxolamine SCHEMBL3498928 | 0.88 | CYP1A2 (1.00) | CYP1A2CYP2D6HIF1AHTR1AHRH3 | |
| Oxolamine SCHEMBL893333 | 0.86 | HTR1A (1.00) | CYP1A2CYP2D6HIF1AHTR1AHRH3 | |
| Oxolamine SCHEMBL1652318 | 0.84 | HTR1A (0.97) | CYP1A2CYP2D6HIF1AHTR1AHRH3 | |
| Oxeladin SCHEMBL28086122 | 0.80 | CYP1A2 (0.60) | CYP1A2CYP2D6HIF1AHTR1AHRH3 | |
| SCHEMBL7947228 | 0.72 | HTR1A (0.73) | CYP1A2CYP2D6HIF1AHTR1AHRH3 | |
| SCHEMBL29376403 | 0.71 | HTR1A (0.71) | CYP1A2CYP2D6HIF1AHTR1AHRH3 | |
| SCHEMBL14288613 | 0.70 | RAB9A (0.70) | CYP1A2HTR1AHRH3ALDH1A1MEN1 | |
| SCHEMBL11983369 | 0.70 | ALDH1A1 (0.69) | CYP1A2CYP2D6HTR1AHRH3ALDH1A1 | |
| SCHEMBL5330405 | 0.70 | ALDH1A1 (0.83) | CYP1A2CYP2D6ALDH1A1MEN1KMT2A | |
| SCHEMBL5331479 | 0.68 | ALDH1A1 (0.69) | CYP1A2CYP2D6HTR1AHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9757376-B2 | Pharmaceutical compositions | GM PHARMACEUTICALS, INC. (US) | 2017-09-12 | — | — | US | claimed |
| EP-1641446-A1 | PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF | Pediamed Pharmaceuticals, Inc. (US) | 2006-04-05 | — | — | EP | claimed |
| WO-2004112771-A1 | PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF | PEDIAMED PHARMACEUTICALS, INC. (US) | 2004-12-29 | — | — | WO | claimed |
| US-20040259809-A1 | Pharmaceutical compositions including an antihistamine and a stimulant and method of use thereof | PEDIAMED PHARMACEUTICALS, INC. | 2004-12-23 | — | — | US | claimed |
| US-10987365-B2 | Compositions and methods for the treatment of pain | GM PHARMACEUTICALS, INC. (US) | 2021-04-27 | — | — | US | disclosed |
| US-9757376-B2 | Pharmaceutical compositions | GM PHARMACEUTICALS, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-20170020873-A1 | PHARMACEUTICAL COMPOSITIONS | GM PHARMACEUTICALS, INC. | 2017-01-26 | — | — | US | disclosed |
| US-9463191-B2 | Pharmaceutical compositions | GM PHARMACEUTICALS, INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-20150265615-A1 | PHARMACEUTICAL COMPOSITIONS | GM PHARMACEUTICALS, INC. | 2015-09-24 | — | — | US | disclosed |
| US-9050289-B2 | Pharmaceutical compositions | GM PHARMACEUTICALS, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20130210835-A1 | PHARMACEUTICAL COMPOSITIONS | GM PHARMACEUTICAL, INC (US) | 2013-08-15 | — | — | US | disclosed |
| US-20090325999-A1 | PERSONALIZED PHARMACEUTICAL KITS, PACKAGING AND COMPOSITIONS FOR THE TREATMENT OF ALLERGIC CONDITIONS | JDP THERAPEUTICS, INC. | 2009-12-31 | — | — | US | disclosed |
| EP-1641446-A1 | PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF | Pediamed Pharmaceuticals, Inc. (US) | 2006-04-05 | — | — | EP | disclosed |
| WO-2004112771-A1 | PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF | PEDIAMED PHARMACEUTICALS, INC. (US) | 2004-12-29 | — | — | WO | disclosed |
| US-20040259809-A1 | Pharmaceutical compositions including an antihistamine and a stimulant and method of use thereof | PEDIAMED PHARMACEUTICALS, INC. | 2004-12-23 | — | — | US | disclosed |