SCHEMBL4414455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4419259	0.92	MAOB (0.53)	EPHX2LDHALDHBMAOAMAOB
	SCHEMBL4419968	0.91	L3MBTL1 (0.46)	MAOBLMNAMEN1KMT2ASMN1; SMN2
	SCHEMBL4422647	0.90	MAOB (0.45)	EPHX2LDHALDHBMAOAMAOB
	SCHEMBL4425190	0.89	MEN1 (0.46)	LMNAMEN1KMT2ASMN1; SMN2HTT
	SCHEMBL4417872	0.89	ALDH1A1 (0.45)	MAOBLMNAMEN1KMT2ASMN1; SMN2
	SCHEMBL4414933	0.89	KMT2A (0.43)	MAOAMAOBLMNAMEN1KMT2A
	SCHEMBL4421518	0.89	MAPT (0.42)	EPHX2MAOAMAOBMEN1KMT2A
	SCHEMBL4415523	0.88	L3MBTL1 (0.44)	LMNAMEN1KMT2ASMN1; SMN2ALDH1A1
	SCHEMBL2182100	0.88	LDHA (0.44)	LDHALDHBMAOAMAOBLMNA
	SCHEMBL4418890	0.88	MEN1 (0.47)	MAOBLMNAMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.