Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 6/20 | 0.38 |
| ▸ | CTSS | P25774 | 6/20 | 0.38 |
| ▸ | CTSK | P43235 | 6/20 | 0.38 |
| ▸ | CTSL | P07711 | 6/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2155717 | 0.86 | CTSK (0.39) | CTSBCTSSCTSKCTSLALOX5 | |
| SCHEMBL2130993 | 0.86 | CTSK (0.47) | CTSBCTSSCTSKCTSLALOX5 | |
| SCHEMBL2156815 | 0.86 | CTSK (0.39) | CTSBCTSSCTSKCTSLALOX5 | |
| SCHEMBL4992329 | 0.86 | CTSK (0.39) | CTSBCTSSCTSKCTSLALOX5 | |
| SCHEMBL2157128 | 0.86 | CTSK (0.39) | CTSBCTSSCTSKCTSLALOX5 | |
| SCHEMBL2157011 | 0.86 | CTSK (0.39) | CTSBCTSSCTSKCTSLALOX5 | |
| SCHEMBL2156797 | 0.86 | CTSK (0.41) | CTSBCTSSCTSKCTSLALOX5 | |
| SCHEMBL2157357 | 0.85 | CTSL (0.38) | CTSBCTSSCTSKCTSLALOX5 | |
| SCHEMBL2133051 | 0.84 | CTSS (0.48) | CTSBCTSSCTSKCTSLALOX5 | |
| SCHEMBL2130906 | 0.83 | CTSL (0.40) | CTSBCTSSCTSKCTSLALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270511-A1 | PRODRUGS OF INHIBITORS OF CATHEPSIN S | MERCK FROSST CANADA LTD. | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270511-A1 | PRODRUGS OF INHIBITORS OF CATHEPSIN S | CTSS, CTSF, CTSB | CTSB 3/4885CTSS 1/4885CTSK 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.