Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PNP | P00491 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414439 | 0.88 | POLB (0.37) | GAALMNAPOLBPNPMEN1 | |
| SCHEMBL5567623 | 0.80 | MEN1 (0.31) | POLBKDM4EMAPTMEN1KMT2A | |
| SCHEMBL4416313 | 0.70 | CYP19A1 (0.37) | MAPTKMT2ACYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL4416377 | 0.63 | ADORA2B (0.62) | ADORA2AADORA2BADORA1 | |
| SCHEMBL7294757 | 0.61 | CYP3A4 (0.52) | LMNAPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL4419731 | 0.60 | TSHR (0.44) | GAALMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL10642210 | 0.59 | PNP (0.78) | PNP | |
| SCHEMBL7618343 | 0.58 | PNP (0.56) | GAALMNAPNPKDM4EMAPT | |
| SCHEMBL9570485 | 0.57 | GPR84 (0.48) | GAAMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL4020067 | 0.56 | MAOB (0.76) | GAAKDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601649-A4 | A1 ADENOSINE RECEPTOR ANTAGONISTS | ENDACEA INC (US) | 2009-03-04 | — | — | EP | claimed |
| EP-1601649-A2 | A1 ADENOSINE RECEPTOR ANTAGONISTS | Endacea Inc. (US) | 2005-12-07 | — | — | EP | claimed |
| WO-2004074247-A2 | A1 ADENOSINE RECEPTOR ANTAGONISTS | ENDACEA, INC. (US) | 2004-09-02 | — | — | WO | claimed |
| EP-1601649-A4 | A1 ADENOSINE RECEPTOR ANTAGONISTS | ENDACEA INC (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1601649-A2 | A1 ADENOSINE RECEPTOR ANTAGONISTS | Endacea Inc. (US) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004074247-A2 | A1 ADENOSINE RECEPTOR ANTAGONISTS | ENDACEA, INC. (US) | 2004-09-02 | — | — | WO | disclosed |