Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29337530 | 0.83 | LTA4H (0.57) | TAAR1CYP17A1CYP11B1CYP11B2ADRA2A | |
| SCHEMBL45228 | 0.80 | LMNA (0.50) | ALDH1A1TSHRTDP1TAAR1ADRA1D | |
| SCHEMBL10525378 | 0.79 | L3MBTL1 (0.55) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL3238290 | 0.79 | LMNA (0.62) | ALDH1A1TAAR1ADRA1DLMNAPTGS1 | |
| SCHEMBL923302 | 0.79 | MEN1 (0.53) | CYP3A4ALDH1A1TSHRTAAR1LMNA | |
| SCHEMBL10953000 | 0.79 | HPGD (0.46) | TSHRTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL3385419 | 0.79 | MEN1 (0.54) | CYP3A4ALDH1A1TAAR1LMNAPTGS1 | |
| SCHEMBL11660485 | 0.79 | TAAR1 (0.42) | TSHRTAAR1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL20738474 | 0.79 | MEN1 (0.61) | ALDH1A1TDP1TAAR1GFERADRA1D | |
| SCHEMBL3236567 | 0.79 | HPGD (0.53) | TAAR1LMNAPTGS1PTGS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020164-A2 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | FIREFLY BIO, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| EP-0353032-B1 | 1,5-BENZOTHIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CARDIOVASCULAR DISORDERS | Sankyo Company Limited (JP) | 1992-02-26 | — | — | EP | disclosed |
| US-5002942-A | Calcium channel blockers for cardiovascular disorders | SANKYO COMPANY, LIMITED (JP) | 1991-03-26 | — | — | US | disclosed |