Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852035 | 0.89 | ALDH1A1 (0.41) | HSD17B10ALDH1A1HIF1ACYP1B1CYP1A2 | |
| SCHEMBL4853742 | 0.87 | CYP1A2 (0.48) | HSD17B10ALDH1A1HIF1ACYP1B1CYP1A2 | |
| SCHEMBL4846793 | 0.86 | CYP1A2 (0.48) | HSD17B10ALDH1A1HIF1ACYP1B1CYP1A2 | |
| SCHEMBL4925761 | 0.82 | ALDH1A1 (0.38) | HSD17B10ALDH1A1HIF1ACYP1B1CYP1A2 | |
| SCHEMBL30879493 | 0.79 | ALDH1A1 (0.50) | HSD17B10ALDH1A1HIF1ACYP1B1CYP1A2 | |
| SCHEMBL25508 | 0.79 | ALDH1A1 (0.50) | HSD17B10ALDH1A1HIF1ACYP1B1CYP1A2 | |
| SCHEMBL4852007 | 0.78 | HSD17B10 (0.60) | HSD17B10ALDH1A1HIF1ACYP1B1CYP1A2 | |
| SCHEMBL9228626 | 0.78 | CYP2A6 (0.47) | HSD17B10ALDH1A1HIF1ACYP1B1CYP1A2 | |
| Benzene SCHEMBL20788840 | 0.78 | ALDH1A1 (0.48) | HSD17B10ALDH1A1HIF1ACYP1B1CYP1A2 | |
| SCHEMBL17417171 | 0.78 | L3MBTL1 (0.35) | HSD17B10ALDH1A1HIF1ACYP1B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521551-B2 | Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-7470290-B2 | Hydroscopic polymer gels for easier cleaning | THE CLOROX COMPANY (US) | 2008-12-30 | — | — | US | disclosed |
| US-20080275232-A1 | CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY | MIRAVANT PHARMACEUTICALS, INC. | 2008-11-06 | — | — | US | disclosed |
| US-7183010-B2 | Organic light-emitting diode devices with improved operational stability | EASTMAN KODAK CORPORATION (US) | 2007-02-27 | — | — | US | disclosed |
| US-20050245428-A1 | Hydroscopic polymer gels for easier cleaning | RODRIGUES KLIN A | 2005-11-03 | — | — | US | disclosed |
| EP-1450774-A4 | CHLORIN PHOTOSENSITIZING AGENTS FOR USE IN PHOTODYNAMIC THERAPY | MIRAVANT PHARM INC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1401430-A4 | SUBSTITUTED PORPHYRIN AND AZAPORPHYRIN DERIVATIVES AND THEIR USE IN PHOTODYNAMIC THERAPY, RADIOIMAGING AND MRI DIAGNOSIS | MIRAVANT PHARM INC (US) | 2005-10-19 | — | — | EP | disclosed |
| US-20050226810-A1 | Substituted porphyrin and azaporphyrin derivatives and their use in photodynamic therapy, radioimaging and MRI diagnosis | MIRAVANT PHARMACEUTICALS, INC. | 2005-10-13 | — | — | US | disclosed |
| US-20050137180-A1 | Metallotetrapyrrolic photosensitizing agents for use in photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. | 2005-06-23 | — | — | US | disclosed |
| US-6906050-B2 | Substituted porphyrin and azaporphyrin derivatives and their use in photodynamic therapy, radioimaging and MRI diagnosis | MIRAVANT PHARMACEUTICALS, INC. (US) | 2005-06-14 | — | — | US | disclosed |
| EP-1450774-A2 | CHLORIN PHOTOSENSITIZING AGENTS FOR USE IN PHOTODYNAMIC THERAPY | Miravant Pharmaceuticals, Inc. (US) | 2004-09-01 | — | — | EP | disclosed |
| US-20040076853-A1 | Organic light-emitting diode devices with improved operational stability | EASTMAN KODAK COMPANY | 2004-04-22 | — | — | US | disclosed |
| EP-1401506-A2 | METALLOTETRAPYRROLIC PHOTOSENSITIZING AGENTS FOR USE IN PHOTODYNAMIC THERAPY | Miravant Pharmaceuticals, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-1401430-A1 | SUBSTITUTED PORPHYRIN AND AZAPORPHYRIN DERIVATIVES AND THEIR USE IN PHOTODYNAMIC THERAPY, RADIOIMAGING AND MRI DIAGNOSIS | Miravant Pharmaceuticals, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| US-20030105069-A1 | Metallotetrapyrrolic photosensitizing agents for use in photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. | 2003-06-05 | — | — | US | disclosed |
| US-20030100752-A1 | Substituted porphyrin and azaporphyrin derivatives and their use in photodynamic therapy, radioimaging and MRI diagnosis | MIRAVANT PHARMACEUTICALS, INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2003028629-A2 | CHLORIN PHOTOSENSITIZING AGENTS FOR USE IN PHOTODYNAMIC THERAPY | MIRAVANT PHARMACEUTICALS, INC. (US) | 2003-04-10 | — | — | WO | disclosed |
| WO-2002096366-A2 | METALLOTETRAPYRROLIC PHOTOSENSITIZING AGENTS FOR USE IN PHOTODYNAMIC THERAPY | MIRAVANT PHARMACEUTICALS, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| WO-2002096417-A1 | SUBSTITUTED PORPHYRIN AND AZAPORPHYRIN DERIVATIVES AND THEIR USE IN PHOTODYNAMIC THERAPY, RADIOIMAGING AND MRI DIAGNOSIS | MIRAVANT PHARMACEUTICALS, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| WO-2001074818-A1 | CHLORINS WITH FUSED RINGS FOR USE IN PHOTODYNAMIC THERAPY | MIRAVANT PHARMACEUTICALS, INC. (US) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275232-A1 | CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY | PPOX, HMBS, DDT | HSD17B10 2961/4885ALDH1A1 1906/4885HIF1A 2595/4885 |
| US-20030100752-A1 | Substituted porphyrin and azaporphyrin derivatives and their use in photodynamic therapy, radioimaging and MRI diagnosis | PPOX, HMBS, MPI | HSD17B10 2933/4885ALDH1A1 1419/4885HIF1A 989/4885 |
| US-20050226810-A1 | Substituted porphyrin and azaporphyrin derivatives and their use in photodynamic therapy, radioimaging and MRI diagnosis | PPOX, HMBS, MPI | HSD17B10 2818/4885ALDH1A1 3401/4885HIF1A 2248/4885 |
| US-20050137180-A1 | Metallotetrapyrrolic photosensitizing agents for use in photodynamic therapy | PPOX, HMBS, PYCR1 | HSD17B10 1706/4885ALDH1A1 1723/4885HIF1A 3931/4885 |
| US-20030105069-A1 | Metallotetrapyrrolic photosensitizing agents for use in photodynamic therapy | PPOX, HMBS, PYCR1 | HSD17B10 1706/4885ALDH1A1 1723/4885HIF1A 3931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.