Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 15/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552231 | 0.81 | CCR5 (0.48) | CCR5KCNH2 | |
| SCHEMBL3749999 | 0.80 | CCR5 (0.50) | CCR5KCNH2 | |
| SCHEMBL3757151 | 0.79 | GPR119 (0.50) | CCR5KCNH2 | |
| SCHEMBL3749922 | 0.78 | CCR5 (0.60) | CCR5KCNH2 | |
| SCHEMBL3749924 | 0.78 | CCR5 (0.65) | CCR5KCNH2 | |
| SCHEMBL4552548 | 0.76 | CCR5 (0.60) | CCR5KCNH2 | |
| SCHEMBL4421630 | 0.75 | CCR5 (0.52) | CCR5KCNH2AGTR2 | |
| SCHEMBL4429198 | 0.74 | CCR5 (0.63) | CCR5KCNH2 | |
| SCHEMBL3763901 | 0.74 | DRD2 (0.46) | CCR5KCNH2 | |
| SCHEMBL4551934 | 0.74 | CCR5 (0.65) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088860-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |