Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | GNG2 | P59768 | 2/20 | 0.46 |
| ▸ | GNB1 | P62873 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439264 | 0.88 | HSD17B10 (0.64) | NR4A2NCF1HSD17B10ALDH1A1CASP1 | |
| SCHEMBL22828432 | 0.84 | POLB (0.51) | HSD17B10ALDH1A1NPC1RAB9AALOX15 | |
| SCHEMBL438970 | 0.81 | NR4A2 (0.60) | NR4A2NCF1HSD17B10ALDH1A1CASP1 | |
| SCHEMBL441705 | 0.79 | CTSS (0.45) | HSD17B10NPC1RAB9AALOX15BLM | |
| SCHEMBL8180035 | 0.76 | CYP1A2 (0.50) | HSD17B10NPC1RAB9AALOX15BLM | |
| SCHEMBL30682591 | 0.74 | NR4A2 (0.64) | NR4A2NCF1HSD17B10ALDH1A1CASP1 | |
| SCHEMBL442339 | 0.74 | NR4A2 (0.64) | NR4A2NCF1HSD17B10ALDH1A1CASP1 | |
| SCHEMBL28348548 | 0.73 | GPR3 (0.51) | HSD17B10NPC1RAB9AALOX15BLM | |
| SCHEMBL21225586 | 0.72 | PDE10A (0.46) | HSD17B10NPC1RAB9AALOX15BLM | |
| SCHEMBL32685110 | 0.71 | CYP1A2 (0.52) | NCF1HSD17B10NPC1RAB9AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |