Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 8/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413049 | 0.91 | TXNRD1 (0.38) | TXNRD1OPRM1OPRD1CHRNB2CHRNB4 | |
| SCHEMBL4419003 | 0.86 | TXNRD1 (0.35) | TXNRD1OPRM1OPRD1CHRNB2CHRNB4 | |
| SCHEMBL4413045 | 0.84 | OPRM1 (0.35) | TXNRD1OPRM1OPRD1CHRNB2CHRNB4 | |
| SCHEMBL4423998 | 0.81 | KEAP1 (0.35) | KEAP1NFE2L2 | |
| SCHEMBL4413065 | 0.76 | TXNRD1 (0.42) | TXNRD1OPRM1OPRD1 | |
| SCHEMBL4427994 | 0.76 | DNM1 (0.41) | TXNRD1OPRM1OPRD1 | |
| SCHEMBL4418549 | 0.76 | ACHE (0.38) | ACHETSHR | |
| SCHEMBL4418406 | 0.76 | DNM1 (0.41) | TXNRD1OPRM1OPRD1 | |
| SCHEMBL4420951 | 0.75 | PHLPP2 (0.46) | TXNRD1SIGMAR1ACHETSHR | |
| SCHEMBL4427273 | 0.74 | DNM1 (0.39) | TXNRD1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620475-B1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2009-11-11 | — | — | EP | disclosed |
| US-7462650-B2 | Trifunctional photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-12-09 | — | — | US | disclosed |
| US-20060270748-A1 | Novel trifunctional photoinitiators | IGM GROUP B.V. (NL) | 2006-11-30 | — | — | US | disclosed |
| EP-1620475-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099262-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-11-18 | — | — | WO | disclosed |