Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | TERT | O14746 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CASP7 | P55210 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440060 | 0.84 | BCHE (0.50) | LMNAMAPTKDM4EMAP4K4 | |
| SCHEMBL439021 | 0.82 | KMT2A (0.55) | KMT2AMEN1BLMTERTABCB11 | |
| SCHEMBL21281225 | 0.81 | MEN1 (0.53) | KMT2AMEN1BLMTERTABCB11 | |
| SCHEMBL436589 | 0.78 | ALDH1A1 (0.46) | KMT2AMEN1LMNAALDH1A1HSD17B10 | |
| SCHEMBL437175 | 0.78 | NPC1 (0.44) | BLMLMNAHSD17B10TP53CYP3A4 | |
| SCHEMBL439500 | 0.77 | ALDH1A1 (0.60) | KMT2AMEN1BLMTERTABCB11 | |
| SCHEMBL440082 | 0.76 | LMNA (0.47) | KMT2AMEN1LMNAALDH1A1HSD17B10 | |
| SCHEMBL437781 | 0.75 | MAPT (0.61) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL439464 | 0.75 | NR4A2 (0.55) | MAP4K4CYP1A2 | |
| SCHEMBL16554120 | 0.74 | MEN1 (0.76) | KMT2AMEN1BLMTERTABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |