Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.46 |
| ▸ | TNF | P01375 | 3/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442268 | 0.86 | ACHE (0.46) | LMNAACHEBCHEGRIN1GRIN2A | |
| SCHEMBL1026768 | 0.86 | ACHE (0.40) | LMNAACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9380208 | 0.81 | LMNA (0.50) | LMNATNFPARP1HTR1AADRA1D | |
| SCHEMBL439464 | 0.81 | NR4A2 (0.55) | ACHEBCHEGRIN1GRIN2APARP1 | |
| SCHEMBL442244 | 0.79 | ACHE (0.43) | LMNAACHEBCHEGRIN1GRIN2A | |
| SCHEMBL439645 | 0.79 | ACHE (0.46) | LMNAACHEBCHEGRIN1GRIN2A | |
| SCHEMBL442137 | 0.79 | HTT (0.49) | LMNAACHEBCHEGRIN1GRIN2A | |
| SCHEMBL440060 | 0.78 | BCHE (0.50) | LMNAACHEBCHEGRIN1GRIN2A | |
| SCHEMBL436589 | 0.78 | ALDH1A1 (0.46) | LMNASMN1; SMN2POLBHTTHIF1A | |
| SCHEMBL26199339 | 0.78 | PARP1 (0.43) | LMNAACHEBCHEGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |