Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915938 | 0.93 | NPC1 (0.46) | NPC1POLBMAPTALDH1A1RBP4 | |
| SCHEMBL4419886 | 0.80 | NPC1 (0.47) | NPC1POLBMAPTALDH1A1RBP4 | |
| Acetonitrile SCHEMBL28767810 | 0.75 | NPC1 (0.42) | NPC1POLBMAPTALDH1A1RBP4 | |
| SCHEMBL27336380 | 0.72 | NPC1 (0.45) | NPC1POLBMAPTALDH1A1RBP4 | |
| SCHEMBL2015042 | 0.72 | LMNA (0.50) | GAACTNNB1WNT3A | |
| SCHEMBL13760452 | 0.72 | NPC1 (0.47) | NPC1POLBMAPTALDH1A1RBP4 | |
| SCHEMBL27743576 | 0.71 | NPC1 (0.55) | NPC1POLBMAPTALDH1A1RBP4 | |
| SCHEMBL7102448 | 0.71 | ROCK2 (0.47) | NPC1POLBMAPTALDH1A1GAA | |
| SCHEMBL7099800 | 0.71 | KDM4C (0.36) | MAPTALDH1A1GAASLC22A12 | |
| SCHEMBL15514535 | 0.70 | NPC1 (0.54) | NPC1POLBMAPTALDH1A1RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507761-B1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | MERIAL INC (US) | 2016-02-24 | — | — | EP | disclosed |
| US-7476685-B2 | Pyridine carboxamide derivatives and their use as pesticides | MERIAL LIMITED (US) | 2009-01-13 | — | — | US | disclosed |
| US-20060166991-A1 | Pyridine carboxamide derivatives and their use as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1507761-A1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | Bayer CropScience GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003097604-A9 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2004-05-06 | — | — | WO | disclosed |
| WO-2003097604-A1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166991-A1 | Pyridine carboxamide derivatives and their use as pesticides | DDT, ACHE, CYCS | NPC1 4667/4885POLB 4540/4885MAPT 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.