Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroethanol SCHEMBL4421337 | 0.93 | NPC1 (0.41) | NPC1POLBRBP4MAPTALDH1A1 | |
| SCHEMBL4419886 | 0.86 | NPC1 (0.47) | NPC1POLBRBP4MAPTALDH1A1 | |
| Acetonitrile SCHEMBL28767810 | 0.80 | NPC1 (0.42) | NPC1POLBRBP4MAPTALDH1A1 | |
| SCHEMBL27336380 | 0.78 | NPC1 (0.45) | NPC1POLBRBP4MAPTALDH1A1 | |
| SCHEMBL2015042 | 0.78 | LMNA (0.50) | GAALMNA | |
| SCHEMBL13760452 | 0.77 | NPC1 (0.47) | NPC1POLBRBP4MAPTALDH1A1 | |
| SCHEMBL27743576 | 0.77 | NPC1 (0.55) | NPC1POLBRBP4MAPTALDH1A1 | |
| SCHEMBL7102448 | 0.76 | ROCK2 (0.47) | NPC1POLBMAPTALDH1A1GAA | |
| SCHEMBL7099800 | 0.76 | KDM4C (0.36) | MAPTALDH1A1GAATDP1SIRT3 | |
| SCHEMBL15514535 | 0.75 | NPC1 (0.54) | NPC1POLBRBP4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507761-B1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | MERIAL INC (US) | 2016-02-24 | — | — | EP | claimed |
| US-20060166991-A1 | Pyridine carboxamide derivatives and their use as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2006-07-27 | — | — | US | claimed |
| EP-1507761-A1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | Bayer CropScience GmbH (DE) | 2005-02-23 | — | — | EP | claimed |
| WO-2003097604-A9 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2004-05-06 | — | — | WO | claimed |
| WO-2003097604-A1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-11-27 | — | — | WO | claimed |
| EP-1507761-B1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | MERIAL INC (US) | 2016-02-24 | — | — | EP | disclosed |
| US-7560456-B2 | Pesticidal pyridinecarboxamide derivatives | MERIAL LIMITED (US) | 2009-07-14 | — | — | US | disclosed |
| US-7476685-B2 | Pyridine carboxamide derivatives and their use as pesticides | MERIAL LIMITED (US) | 2009-01-13 | — | — | US | disclosed |
| US-20070010532-A1 | 3-Pyridylcarboxamide derivatives as pesticidal agents | BAYER CROPSCIENCE GMBH (DE) | 2007-01-11 | — | — | US | disclosed |
| CN-1845919-A | 3-pyridylcarboxamide derivatives as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2006-10-11 | — | — | CN | disclosed |
| EP-1507762-B1 | PESTICIDAL PYRIDINECARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2006-08-02 | — | — | EP | disclosed |
| US-20060166991-A1 | Pyridine carboxamide derivatives and their use as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1644354-A1 | 3-PYRIDYLCARBOXAMIDE DERIVATIVES AS PESTICIDAL AGENTS | Bayer CropScience GmbH (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20050227970-A1 | Pesticidal pyridinecarboxamide derivatives | MERIAL LIMITED | 2005-10-13 | — | — | US | disclosed |
| EP-1507762-A1 | PESTICIDAL PYRIDINECARBOXAMIDE DERIVATIVES | Bayer CropScience GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |
| EP-1507761-A1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | Bayer CropScience GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |
| WO-2005005412-A1 | 3-PYRIDYLCARBOXAMIDE DERIVATIVES AS PESTICIDAL AGENTS | BAYER CROPSCIENCE GMBH (DE) | 2005-01-20 | — | — | WO | disclosed |
| WO-2003097604-A9 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2004-05-06 | — | — | WO | disclosed |
| WO-2003097604-A1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-11-27 | — | — | WO | disclosed |
| WO-2003097605-A1 | PESTICIDAL PYRIDINECARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166991-A1 | Pyridine carboxamide derivatives and their use as pesticides | DDT, ACHE, CYCS | NPC1 4667/4885POLB 4540/4885RBP4 3063/4885 |
| US-20050227970-A1 | Pesticidal pyridinecarboxamide derivatives | DDT, ACHE, PTMS | NPC1 4676/4885POLB 4749/4885RBP4 4011/4885 |
| US-20070010532-A1 | 3-Pyridylcarboxamide derivatives as pesticidal agents | DDT, PLPBP, ACHE | NPC1 4590/4885POLB 4556/4885RBP4 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.