Known targets — ChEMBL curated mechanism
DHFRGARTPTGFRPTGIRPTGS1PTGS2TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8envmurAthyA
The experimentally established mechanism targets of Tromethamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tromethamine SCHEMBL21111803 | 0.79 | MEN1 (0.39) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL6416973 | 0.78 | MEN1 (0.42) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL21224900 | 0.78 | MEN1 (0.42) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL4927868 | 0.78 | MEN1 (0.42) | MEN1LMNAKMT2A | |
| SCHEMBL1085520 | 0.77 | — | — | |
| Tromethamine SCHEMBL21111787 | 0.75 | MEN1 (0.39) | MEN1LMNAKMT2A | |
| SCHEMBL28308447 | 0.74 | — | — | |
| Tromethamine SCHEMBL342628 | 0.74 | MEN1 (0.71) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL845321 | 0.73 | MEN1 (0.53) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL21111811 | 0.71 | MEN1 (0.34) | MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122051388-A | Electrolyte, lithium secondary battery, and method for forming lithium secondary battery | 北京卫蓝新能源科技股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122051335-A | Lithium ion battery and power utilization device | 中创新航科技集团股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122010154-A | Method for preparing high-whiteness cubic nano calcium carbonate at low temperature | 湖北三峡实验室 | 2026-05-12 | — | — | CN | claimed |
| CN-122029627-A | Electrolyte composition for sodium-based battery and method for manufacturing same | 科罗拉多州立大学董事会 | 2026-05-12 | — | — | CN | claimed |
| CN-122025807-A | Secondary battery, battery module, battery pack, and power consumption device | 宁德时代新能源科技股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-121583784-A | Electrolyte capable of inhibiting decomposition of super capacitor binder, and preparation method and application thereof | 今朝时代(安徽)新能源科技有限公司 | 2026-02-27 | — | — | CN | claimed |
| US-20250266446-A1 | LITHIUM ION BATTERY | SHENZHEN CAPCHEM TECHNOLOGY CO., LTD. (CN) | 2025-08-21 | — | — | US | claimed |
| CN-120199893-A | Electrolyte additive composition, nonaqueous electrolyte containing same and secondary battery | 深圳市研一新材料有限责任公司 | 2025-06-24 | — | — | CN | claimed |
| CN-115799641-B | Lithium ion battery, preparation method thereof and electric equipment | 欣旺达动力科技股份有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-120157699-A | Preparation method of tri (trimethylsilane) borate | 江苏国泰超威新材料有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-111313091-A | Electrolyte solution, electrochemical device, and electronic device | 宁德新能源科技有限公司 | 2020-06-19 | — | — | CN | claimed |
| CN-111276746-A | Electrochemical device and electronic device comprising same | 宁德新能源科技有限公司 | 2020-06-12 | — | — | CN | claimed |
| CN-111244545-A | Overcharge-preventing electrolyte and lithium ion battery using same | 珠海冠宇电池有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-111129587-A | Non-aqueous electrolyte for lithium ion battery and lithium ion battery thereof | 杉杉新材料（衢州）有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-111060608-A | Method for detecting alkyl silicon compounds in lithium ion battery electrolyte | 合肥国轩高科动力能源有限公司 | 2020-04-24 | — | — | CN | claimed |
| CN-111029654-A | Electrolyte and lithium ion battery using same | 杉杉新材料（衢州）有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-110945704-A | Electrolyte for secondary battery and secondary battery comprising the same | 株式会社LG化学 | 2020-03-31 | — | — | CN | claimed |
| CN-107666007-B | Non-aqueous electrolyte of lithium ion battery and lithium ion battery | 比亚迪股份有限公司 | 2020-03-31 | — | — | CN | claimed |
| CN-110627830-A | Disodium p-nitrophenylphosphate and preparation method thereof | 安徽昊帆生物有限公司 | 2019-12-31 | — | — | CN | claimed |
| EP-1585142-A1 | Composition for electrolyte, high molecular weight electrolyte, and battery using it | SONY CORPORATION (JP) | 2005-10-12 | — | — | EP | claimed |