Known targets — ChEMBL curated mechanism
DHFRGARTPTGFRPTGIRPTGS1PTGS2TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8envmurAthyA
The experimentally established mechanism targets of Tromethamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837674 | 0.82 | — | — | |
| Boric Acid SCHEMBL28104218 | 0.82 | — | — | |
| Tromethamine SCHEMBL442155 | 0.78 | MEN1 (0.46) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL21111787 | 0.76 | MEN1 (0.39) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL21111811 | 0.76 | MEN1 (0.34) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL21224900 | 0.75 | MEN1 (0.42) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL1312854 | 0.74 | LMNA (0.77) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL21111803 | 0.72 | MEN1 (0.39) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL571834 | 0.68 | MEN1 (0.77) | MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL1019777 | 0.68 | MEN1 (0.77) | MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119725589-A | Lithium carbon fluoride battery | 惠州亿纬锂能股份有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119208736-A | Lithium ion battery | 惠州市豪鹏科技有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-118648152-A | Sodium ion battery electrolyte, sodium ion battery containing same and electricity utilization device | 宁德时代新能源科技股份有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-118281329-A | Nonaqueous electrolyte and secondary battery | 深圳新宙邦科技股份有限公司 | 2024-07-02 | — | — | CN | claimed |
| WO-2024011355-A1 | ELECTROLYTE FOR SODIUM-ION BATTERY, SODIUM-ION BATTERY COMPRISING SAME, AND ELECTRIC DEVICE | 宁德时代新能源科技股份有限公司 | 2024-01-18 | — | — | WO | claimed |
| CN-116135948-A | Chemical etching composition and application thereof | 安集微电子（上海）有限公司 | 2023-05-19 | — | — | CN | claimed |
| CN-115584263-A | Chemical etching composition and application thereof | 安集微电子（上海）有限公司 | 2023-01-10 | — | — | CN | claimed |
| CN-115411363-A | Electrolyte, secondary battery and electric equipment | 欣旺达电动汽车电池有限公司 | 2022-11-29 | — | — | CN | claimed |
| CN-115395079-A | Composite solid electrolyte membrane, preparation method thereof and lithium ion battery | 浙江吉利控股集团有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-109293691-B | Method for preparing lithium bis (oxalato) borate | 常熟市常吉化工有限公司 | 2020-10-16 | — | — | CN | claimed |
| EP-1585142-A1 | Composition for electrolyte, high molecular weight electrolyte, and battery using it | SONY CORPORATION (JP) | 2005-10-12 | — | — | EP | claimed |
| CN-119725589-A | Lithium carbon fluoride battery | 惠州亿纬锂能股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119208736-A | Lithium ion battery | 惠州市豪鹏科技有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-115335455-B | Mixture of polyoxyalkylene polymer and curable composition | 株式会社钟化 | 2024-11-19 | — | — | CN | disclosed |
| CN-118804953-A | Curable composition and use thereof | 株式会社钟化 | 2024-10-18 | — | — | CN | disclosed |
| US-20190214682-A1 | ELECTROLYTE SOLUTION, ELECTROCHEMICAL DEVICE, SECONDARY BATTERY, AND MODULE | DAIKIN INDUSTRIES, LTD. (JP) | 2019-07-11 | — | — | US | disclosed |
| US-20170051108-A1 | POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME | KANEKA CORPORATION (JP) | 2017-02-23 | — | — | US | disclosed |
| CN-101188313-B | Electrolyte for rechargeable lithium battery, and rechargeable lithium battery including same | SAMSUNG SDI CO LTD | 2010-12-29 | — | — | CN | disclosed |
| CN-101188313-A | Electrolyte for rechargeable lithium battery, and rechargeable lithium battery including same | SAMSUNG SDI CO LTD (KR) | 2008-05-28 | — | — | CN | disclosed |
| EP-1585142-A1 | Composition for electrolyte, high molecular weight electrolyte, and battery using it | SONY CORPORATION (JP) | 2005-10-12 | — | — | EP | disclosed |