Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438745 | 0.88 | KEAP1 (0.49) | KEAP1DHODHALDH1A1GAAHAVCR2 | |
| SCHEMBL16621492 | 0.83 | HAVCR2 (0.47) | ALDH1A1HAVCR2KMT2AACHEPARP1 | |
| SCHEMBL398640 | 0.83 | DHODH (0.47) | KEAP1DHODHALDH1A1GAARXFP1 | |
| SCHEMBL22395713 | 0.81 | DHODH (0.46) | KEAP1DHODHALDH1A1GAARXFP1 | |
| SCHEMBL7496024 | 0.81 | DHODH (0.46) | KEAP1DHODHALDH1A1GAARXFP1 | |
| SCHEMBL440411 | 0.81 | HAVCR2 (0.52) | DHODHALDH1A1HAVCR2MEN1KMT2A | |
| SCHEMBL442132 | 0.81 | TSHR (0.50) | DHODHALDH1A1GAAHAVCR2RXFP1 | |
| SCHEMBL436603 | 0.81 | KDM4E (0.48) | DHODHALDH1A1GAAHAVCR2MEN1 | |
| SCHEMBL439948 | 0.81 | ALDH1A1 (0.53) | DHODHALDH1A1HAVCR2MEN1KMT2A | |
| SCHEMBL439008 | 0.79 | NMT2 (0.60) | ALDH1A1GAAMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |