Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861434 | 0.98 | APP (0.38) | APPPTGS1PDE4ALMNASLC6A6 | |
| Lithium Ion SCHEMBL3462729 | 0.98 | APP (0.38) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL620882 | 0.98 | APP (0.38) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL8861521 | 0.98 | APP (0.38) | APPPTGS1PDE4ALMNASLC6A6 | |
| Potassium Ion SCHEMBL444305 | 0.94 | APP (0.38) | APPPTGS1PDE4ALMNASLC6A6 | |
| Tetramethylammonium Ion SCHEMBL3462398 | 0.92 | APP (0.34) | APP | |
| Potassium Ion SCHEMBL11801333 | 0.92 | APP (0.37) | APPPTGS1PDE4ALMNASLC6A6 | |
| Potassium Ion SCHEMBL16010564 | 0.92 | APP (0.37) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL17476621 | 0.92 | APP (0.37) | APPPTGS1PDE4ALMNASLC6A6 | |
| Potassium Ion SCHEMBL16009057 | 0.92 | APP (0.37) | APPPTGS1PDE4ALMNASLC6A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023124736-A1 | X-RAY DEVELOPABLE MOLECULE, X-RAY DEVELOPABLE EMBOLIC MICROSPHERE AND PREPARATION METHOD THEREFOR | 上海汇禾医疗科技有限公司 | 2023-07-06 | — | — | WO | claimed |
| CN-115869460-A | Nano gel self-adhesive powder for wound antibiosis and hemostasis and preparation method thereof | 浙江工业大学 | 2023-03-31 | — | — | CN | claimed |
| US-11572429-B2 | Hydrogels based on vinyl-caprolactam | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) | 2023-02-07 | — | — | US | claimed |
| US-11285239-B2 | Absorbent articles containing a multifunctional gel | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2022-03-29 | — | — | US | claimed |
| CN-113354765-A | Viscosity-reducing polycarboxylate superplasticizer and preparation method thereof | 武汉优城科技有限公司 | 2021-09-07 | — | — | CN | claimed |
| EP-3778675-A1 | HYDROGELS BASED ON VINYL CAPROLACTAM | Consejo Superior de Investigaciones Cientificas (CSIC) (ES) | 2021-02-17 | — | — | EP | claimed |
| US-20210017316-A1 | Hydrogels Based on Vinyl-Caprolactam | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2021-01-21 | — | — | US | claimed |
| EP-3142744-B1 | A STIMULATION ELECTRODE | SOOMA LTD (FI) | 2020-03-04 | — | — | EP | claimed |
| US-10456139-B2 | Seal element for anastomosis | COVIDIEN LP (US) | 2019-10-29 | — | — | US | claimed |
| WO-2019193236-A1 | HYDROGELS BASED ON VINYL CAPROLACTAM | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2019-10-10 | — | — | WO | claimed |
| US-20060085030-A1 | Seal element for anastomosis | COVIDIEN LP | 2006-04-20 | — | — | US | claimed |
| WO-2006023444-A2 | ANTI-ADHESION BARRIER | TYCO HEALTHCARE GROUP, LP (US) | 2006-03-02 | — | — | WO | claimed |
| WO-2006023578-A2 | STAPLING SUPPORT STRUCTURES | TYCO HEALTHCARE GROUP, LP (US) | 2006-03-02 | — | — | WO | claimed |
| WO-2006023486-A1 | WATER-SWELLABLE COPOLYMERS AND ARTICLES AND COATING MADE THEREFROM | TYCO HEALTHCARE GROUP, LP (US) | 2006-03-02 | — | — | WO | claimed |
| EP-0676457-B1 | Poly(meth)acrylate ester based hydrogel adhesives | GRAPHIC CONTROLS CORP (US) | 1998-10-07 | — | — | EP | claimed |
| US-5674275-A | FOR ADHERING BIOMEDICAL DEVICES TO SKIN | GRAPHIC CONTROLS CORPORATION (US) | 1997-10-07 | — | — | US | claimed |
| US-5614586-A | CROSSLINKED ACRYLATE ADHESIVE WITH SULFONATE, CARBOXYLATE OR AMMONIUM GROUPS | GRAPHIC CONTROLS CORPORATION (US) | 1997-03-25 | — | — | US | claimed |
| US-5612161-A | Negatively chargable toner for electrophotography | FUJIKURA KASEI CO., LTD. (JP) | 1997-03-18 | — | — | US | claimed |
| EP-0676457-A1 | Poly(meth)acrylate ester based hydrogel adhesives | GRAPHIC CONTROLS CORPORATION (US) | 1995-10-11 | — | — | EP | claimed |
| US-4319014-A | UNDATURATED CARBOXYLIC ACID COPOLYMER WITH UNDATURATED SULFONATE COMONOMER MODIFIED BY A MERCAPTAN | UNIROYAL, INC. (US) | 1982-03-09 | — | — | US | claimed |