Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595948 | 0.80 | BACE1 (0.36) | CHRM3GRIN1GRIN2AGRIN2B | |
| SCHEMBL4415834 | 0.80 | BACE1 (0.36) | CHRM3GRIN1GRIN2AGRIN2B | |
| SCHEMBL4597510 | 0.71 | KDM4E (0.32) | CHRM3ALDH1A1 | |
| SCHEMBL4596041 | 0.71 | KDM4E (0.32) | CHRM3ALDH1A1 | |
| SCHEMBL4597467 | 0.70 | KDM4E (0.31) | — | |
| SCHEMBL4626507 | 0.69 | NSD3 (0.36) | SIGMAR1CHRM3ALDH1A1 | |
| SCHEMBL4610698 | 0.69 | NSD3 (0.36) | SIGMAR1CHRM3ALDH1A1 | |
| SCHEMBL5179386 | 0.69 | GRIN1 (0.38) | SIGMAR1CHRM3ALDH1A1GRIN1GRIN2A | |
| SCHEMBL4596721 | 0.67 | CHRM2 (0.37) | SIGMAR1CHRM3CNR2 | |
| SCHEMBL4596366 | 0.67 | CHRM2 (0.37) | SIGMAR1CHRM3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088860-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |