Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.33 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4626507 | 1.00 | NSD3 (0.36) | NSD3KDM1AMAOAKDM4EHTR6 | |
| SCHEMBL4552557 | 0.85 | OPRM1 (0.34) | CHRM2CHRM3OPRM1 | |
| SCHEMBL5179386 | 0.79 | GRIN1 (0.38) | NSD3KDM1AMAOAKDM4EHTR6 | |
| SCHEMBL4415834 | 0.78 | BACE1 (0.36) | NSD3KDM4ECHRM2CHRM3 | |
| SCHEMBL4595948 | 0.78 | BACE1 (0.36) | NSD3KDM4ECHRM2CHRM3 | |
| SCHEMBL4597510 | 0.76 | KDM4E (0.32) | NSD3KDM1AMAOAKDM4ECHRM3 | |
| SCHEMBL4596041 | 0.76 | KDM4E (0.32) | NSD3KDM1AMAOAKDM4ECHRM3 | |
| SCHEMBL4597467 | 0.74 | KDM4E (0.31) | NSD3KDM4EPRKCGPRKCBPRKCA | |
| SCHEMBL4598182 | 0.73 | GRIN1 (0.36) | NSD3KDM1AMAOAKDM4ECHRM2 | |
| SCHEMBL4429230 | 0.73 | MMP2 (0.35) | NSD3KDM1AMAOAKDM4EOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |