Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | PRKCB | P05771 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCH | P24723 | 1/20 | 0.30 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.30 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.30 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.30 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597579 | 0.87 | DRD2 (0.33) | — | |
| SCHEMBL4597510 | 0.83 | KDM4E (0.32) | KDM4ENSD3 | |
| SCHEMBL4596041 | 0.83 | KDM4E (0.32) | KDM4ENSD3 | |
| SCHEMBL4595948 | 0.83 | BACE1 (0.36) | KDM4ENSD3 | |
| SCHEMBL4415834 | 0.83 | BACE1 (0.36) | KDM4ENSD3 | |
| SCHEMBL5179386 | 0.74 | GRIN1 (0.38) | KDM4ENSD3 | |
| SCHEMBL4610698 | 0.74 | NSD3 (0.36) | KDM4ENSD3PRKCGPRKCBPRKCA | |
| SCHEMBL4626507 | 0.74 | NSD3 (0.36) | KDM4ENSD3PRKCGPRKCBPRKCA | |
| SCHEMBL4596366 | 0.71 | CHRM2 (0.37) | — | |
| SCHEMBL4596721 | 0.71 | CHRM2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |