Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 4/20 | 0.39 |
| ▸ | KDM4A | O75164 | 4/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.39 |
| ▸ | HIF1AN | Q9NWT6 | 4/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM3B | Q7LBC6 | 4/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439660 | 0.84 | KDM4E (0.41) | KDM4ENAPRTKMT2AMEN1GAA | |
| SCHEMBL4430946 | 0.84 | HSD17B2 (0.46) | KDM4EKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL4428254 | 0.82 | HSD17B2 (0.49) | KDM4EKMT2AMEN1ALDH1A1HSD17B2 | |
| SCHEMBL4429520 | 0.81 | KDM4E (0.42) | KDM4ENAPRTPOLBALDH1A1GAA | |
| SCHEMBL4431362 | 0.80 | KDM4E (0.46) | KDM4ENAPRTKMT2AALDH1A1GAA | |
| SCHEMBL4428130 | 0.80 | KDM4E (0.46) | KDM4ENAPRTKMT2AALDH1A1GAA | |
| SCHEMBL5124119 | 0.77 | KDM4E (0.49) | KDM4ENAPRTPOLBALDH1A1GAA | |
| SCHEMBL3071414 | 0.77 | KDM4E (0.49) | KDM4ENAPRTKMT2APOLBALDH1A1 | |
| SCHEMBL4430955 | 0.71 | KDM4E (0.47) | KDM4ENAPRTALDH1A1KDM6BKDM4A | |
| Phthalic Acid SCHEMBL30249230 | 0.71 | ALDH1A1 (0.70) | KDM4ENAPRTKMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125739-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008079371-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |